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Caspase 6 Antikörper (N-Term)

CASP6 Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499571
  • Target Alle Caspase 6 (CASP6) Antikörper anzeigen
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Bindungsspezifität
    • 26
    • 16
    • 15
    • 12
    • 10
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 137
    • 78
    • 36
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 159
    • 10
    • 1
    Kaninchen
    Klonalität
    • 148
    • 22
    Polyklonal
    Konjugat
    • 75
    • 16
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Caspase 6 Antikörper ist unkonjugiert
    Applikation
    • 137
    • 68
    • 61
    • 41
    • 40
    • 30
    • 26
    • 16
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    Caspase-6 antibody was raised against a 15 amino acid peptide from near the amino-terminus of human Caspase-6.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Virus Casp-6 / Mch2 (N-Terminus) Peptide
    Isotyp
    IgG
    Top Product
    Discover our top product CASP6 Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: Caspase-6 antibody can be used for the detection of caspase-6 at 0.5 μg/mL. Depending on cell lines or tissues used, either full-length or other cleavage products maybe observed. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
    Andere Bezeichnung
    Caspase-6 (CASP6 Produkte)
    Synonyme
    xCaspase-6 antikoerper, mch2 antikoerper, caspase-6 antikoerper, zgc:112960 antikoerper, CASP6 antikoerper, casp6 antikoerper, Mch2 antikoerper, mCASP-6 antikoerper, MCH2 antikoerper, caspase 6 L homeolog antikoerper, caspase 6 antikoerper, caspase 6, apoptosis-related cysteine peptidase antikoerper, group XIIA secretory phospholipase A2 antikoerper, caspase-6 antikoerper, casp6.L antikoerper, casp6 antikoerper, CASP6 antikoerper, CpipJ_CPIJ017008 antikoerper, Casp6 antikoerper
    Hintergrund
    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-6 is an executioner caspase that was idientifed based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3 (4). It possesses two isoforms, of which only the longer form possesses protease activity (4). Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies (5).Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
    Gen-ID
    839
    NCBI Accession
    NP_001217
    UniProt
    P55212
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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