CHEK1 Antikörper (AA 312-327)
Kurzübersicht für CHEK1 Antikörper (AA 312-327) (ABIN401324)
Target
Alle CHEK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 312-327
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Spezifität
- This antibody is directed against yeast CHK1 protein.
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Aufreinigung
- Affinity chromatography
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Immunogen
- Synthetic peptide corresponding aa 312-327 of S. cerevisiae CHK1
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Isotyp
- IgG
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Applikationshinweise
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.73 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Andere Bezeichnung
- CHK1
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Hintergrund
- CHK1 (also known as serine/threonine-protein kinase CHK1 and checkpoint kinase 1) is involved in cell cycle arrest when DNA damage has occurred or when unligated DNA is present. The kinase controls phosphorylation and abundance of PDS1 to prevent anaphase entry. Also helps prevent mitotic exit. CHK1 is localized within the nucleus.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1
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Gen-ID
- 852577
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NCBI Accession
- NP_009833
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UniProt
- P38147
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Pathways
- p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
Target
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