CSNK1A1 Antikörper (C-Term)

Produktnummer ABIN391597

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CSNK1A1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für CSNK1A1 Antikörper (C-Term) (ABIN391597)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSNK1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB00886

Produktdetails anti-CSNK1A1 Antikörper

Bindungsspezifität: AA 309-337, C-Term

Homologie: C, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CSNK1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-337 amino acids from the C-terminal region of human CSNK1A1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CSNK1A1 Antikörper (ABIN391597)

Rodriguez, Yang, Hasselblatt, Liu, Zhou, Rauh-Hain, Ng, Choi, Fong, Agar, Welch, Berkowitz, Ng: "Casein kinase I epsilon interacts with mitochondrial proteins for the growth and survival of human ovarian cancer cells." in: EMBO molecular medicine, Vol. 4, Issue 9, pp. 952-63, (2012) (PubMed).

Details zu CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Andere Bezeichnung: CK1a

Hintergrund: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.

Molekulargewicht: 38915

Gen-ID: 1452

NCBI Accession: NP_001020276, NP_001258670, NP_001258671, NP_001883

UniProt: P48729

Pathways: WNT Signalweg, Hedgehog Signalweg