BCL10 (AA 122-168) Antikörper
| Antigen |
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| Klonalität |
Monoklonal (151) |
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Wirt
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Reaktivität
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| Produktnummer |
ABIN379257 |
| Menge |
1 ml (Varianten) |
| Preis |
435,90 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
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Swiss-Prot
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O95999
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Immunogen
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Human recombinant Bcl-10.
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Isotyp
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IgG1 (Passende Sekundärantikörper)
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Klon
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151
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Beschreibung
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Gene: BCL10, Standard Gene Symbol: BCL10, Family: Apoptosis, Synonyms: BCL10, c-E10, CARMEN, CIPER, CLAP, mE10
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Spezifität
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Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.
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Reinigung
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Protein G Column
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Buffer
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Sodium azide
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Lagerung
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Store at 2°C to 8°C degrees. Do not freeze.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "BCL10 (AA 122-168)", Typ "Antikörper" finden
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