ELK1 (pSer383) Antikörper

Antigen: ELK1

Epitope: pSer383

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN361487

Produktbeschreibung

Weitere Bezeichnung: Phospho-Ser383 Elk-1

Format: Affinity-purified

Beschreibung: Elk-1 is a transcription factor involved in mediating gene transcription in response to growth factors (Hill and Treisman, 1995). Elk-1 is thought to be phosphorylated by MAP kinase at Ser383 and phosphorylation at this site is essential for the transcriptional activity of Elk-1 (Li et al., 2003). Phosphorylation of Elk-1 has also been implicated in synaptic plasticity in the adult hippocampus (Thiels et al., 2002). Anti-Phospho Ser383 Elk-1 Western blot of recombinant Elk-1 showing specific immunolabeling of the ~46k Elk-1 phosphorylated at Ser383 (Phos). The immunolabeling is absent in dephospho-Elk-1 (Non-Phos).

Spezifität: Specific for ~46k Elk-1 phosphorylated at Ser383. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Reinigung: Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.

Lagerung: Store at -20 °C, stable for 1 year

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of recombinant Elk-1 showing specific immunolabeling of the ~46k Elk-1 phosphorylated at Ser383 (Phos). The immunolabeling is absent in dephospho-Elk-1 (Non-Phos).