Growth Hormone 1 Antikörper

Produktnummer ABIN318574

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Growth Hormone 1 in WB, IF, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Hund, Schaf und Cat.

Kurzübersicht für Growth Hormone 1 Antikörper (ABIN318574)

Target: Growth Hormone 1 (GH1)

Reaktivität: Human, Ratte, Hund, Schaf, Cat

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Growth Hormone 1 Antikörper

Spezifität: This antibody recognizes human Growth Hormone (GH), which acts to control body growth and metabolic activity. In Western blotting a band of approximately 20 kDa is seen using lysates of human pituitary gland.

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Growth hormone from ovine pituitary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/50-1/500. Immunofluorescence: 1/10-1/100. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/500-1/4000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Storage in frost-free freezers is not recommended.

Details zu Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Andere Bezeichnung: Somatotropin / Growth Hormone / GH1

Hintergrund: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expression.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone

Gen-ID: 2688

NCBI Accession: NP_000506

UniProt: P01241

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process