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Zinc Finger Protein GLI1 (GLI1) Antikörper

Antigen

Zinc Finger Protein GLI1 (GLI1)

Synonyme GLI
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Western Blot (WB)
Produktnummer ABIN307152
Menge 100 ug  (1 mg/ml)
Preis 276,92 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung Zinc Finger Protein GLI1
Swiss-Prot P08151
Beschreibung Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes dring normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer. Synonyms: Glioma-associated oncogene, Oncogene GLI.

Anwendungen

Applikationshinweise Antibody can be used for Western blotting (1:400 starting dilution). Positive Control: Protein found in testis, myometrium and fallopian tube..
Konzentration 1 mg/ml
Lagerung Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Zinc Finger Protein GLI1 (GLI1)", Typ "Antikörper" finden
Wirte Kaninchen (17), Ziege (4), Maus (4)
Reaktivitäten Human (20), Maus (5), Rind (Kuh) (2), Hund (2), Pferd (1), Affe (1)
Applikationen Western Blot (WB) (16), Enzyme Immunoassay (EIA) (6), Immunpräzipitation (IP) (3), ELISA (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Dot Blot (Dot) (1)