MALT1 Antikörper (AA 43-57)

Produktnummer ABIN298719

Der Kaninchen Polyklonal anti-MALT1 Antikörper (ABIN298719) detektiert spezifisch MALT1 in WB, IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MALT1 Antikörper (AA 43-57) (ABIN298719)

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MALT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MALT1 Antikörper

Bindungsspezifität: AA 43-57

Spezifität: A synthetic peptide corresponding to amino acids 43-57 (ELLDQAPEGRGWRRL) of human MALT1 (GenBank No. NP_776216.1) was used as immunogen. The immunogen sequence is 100 % conserved between Malt1 isoforms a and b.

Homologie: Percent identity by BLAST analysis: Human (100%) Monkey (93%) Gorilla, Gibbon, Elephant (87%) Marmoset, Bovine, Bat (80%).

Aufreinigung: Protein G purified

Immunogen: A synthetic peptide corresponding to amino acids 43-57 (ELLDQAPEGRGWRRL) of human MALT1 (GenBank No. NP_776216.1). The immunogen sequence is 100% conserved between Malt1 isoforms a and b. Percent identity by BLAST analysis: Human (100%), Monkey (93%), Chimpanzee, Gorilla, Orangutan, Gibbon, Elephant (87%), Galago, Marmoset, Bovine, Cat (80%), Mouse, Rat (73%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (10 μg/mL), WB (0.5 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Andere Bezeichnung: MALT1

Hintergrund: Name/Gene ID: MALT1
Subfamily: Cysteine C14
Family: Protease

Synonyms: MALT1, Caspase-like protein, MLT, MLT1, Paracaspase, MALT associated translocation

Gen-ID: 10892

NCBI Accession: NP_776216

UniProt: Q9UDY8

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine