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zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) (pTyr493) Antikörper
| Antigen | zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70) |
| Synonyme | SRK, STD, TZK, ZAP-70, FLJ17670, FLJ17679, Srk, mur, 70kDa, mrtle, AI327364, MGC108902, zap70, MGC80670, MGC88962, ZAP70 |
| Epitope |
Alternativen pTyr493 |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
|
| Produktnummer | ABIN196887 |
| Menge | 50 µg (1.0 mg/ml) (Varianten) |
| Preis | 220,00 € Zzgl. Versandkosten €40,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Produktmerkmale | Synonyms: ZAP-70, ZAP 70, SRK, 70 kDa zeta-associated protein, Syk-related tyrosine kinase |
| Weitere Bezeichnung | ZAP70 |
| Swiss-Prot | P43403 |
| Kreuzreaktivität | Human, Maus, Ratte (Rattus) |
| Beschreibung | ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role inlymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined ImmunodeficiencySyndrome (SCID) in humans. ZAP70 expression also defines a subset of ChronicLymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course. |
| Spezifität | This antibody detects endogenous levels of Zap-70 only when phosphorylated at Tyrosine493. Species: Human, Mouse and Rat. Others not tested. |
Anwendungen
| Applikationshinweise | Western Blot 1/500-1/1000). Immunohistochemistry on Paraffin-Embedded Sections (1/50-1/100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Konzentration | 1.0 mg/ml |
| Reinigung | Aff - Purified |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azideand 50% Glycerol. |
| Lagerung | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Bilder
| Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Zap-70 (phospho-Tyr493) antibody (). |
Alternativen
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