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MAP2K6 Antikörper (pSer207)

MAP2K6 Reaktivität: Human, Ratte WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN196864
  • Target Alle MAP2K6 Antikörper anzeigen
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Bindungsspezifität
    • 19
    • 15
    • 11
    • 9
    • 9
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer207
    Reaktivität
    • 74
    • 63
    • 39
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 88
    • 6
    • 2
    Kaninchen
    Klonalität
    • 90
    • 6
    Polyklonal
    Konjugat
    • 47
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MAP2K6 Antikörper ist unkonjugiert
    Applikation
    • 83
    • 41
    • 27
    • 27
    • 16
    • 14
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of MKK6 only when phosphorylated at serine207.
    Aufreinigung
    Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Synthetic phosphopeptide derived from Human MKK6 around the phosphorylation site of Serine 207 (V-D-Sp-V-A).
    Top Product
    Discover our top product MAP2K6 Primärantikörper
  • Applikationshinweise
    Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Andere Bezeichnung
    MAP2K6 (MAP2K6 Produkte)
    Synonyme
    MAPKK6 antikoerper, MEK6 antikoerper, MKK6 antikoerper, PRKMK6 antikoerper, SAPKK-3 antikoerper, SAPKK3 antikoerper, Mkk6 antikoerper, Prkmk6 antikoerper, MKK3 antikoerper, map2k3 antikoerper, zMKK3 antikoerper, map2k6 antikoerper, mitogen-activated protein kinase kinase 6 antikoerper, mitogen-activated protein kinase kinase 6 L homeolog antikoerper, MAP2K6 antikoerper, Map2k6 antikoerper, map2k6 antikoerper, map2k6.L antikoerper
    Hintergrund
    Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.Synonyms: Dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6, MAPK/ERK kinase 6, MAPKK 6, MEK6, MKK6, SAPKK3
    Gen-ID
    5608
    NCBI Accession
    NP_002749
    UniProt
    P52564
    Pathways
    MAPK Signalweg, TLR Signalweg, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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