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Protein-tyrosine Phosphatase 1C (PTPN6) (internal) Antikörper
| Antigen | Protein-tyrosine Phosphatase 1C (PTPN6) |
| Synonyme | HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1 |
| Epitope |
 Alternativen internal |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Ziege |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen ELISA, Western Blot (WB)
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1 Publikation vorhanden |
| Produktnummer | ABIN190820 |
| Menge | 100 ug (Varianten) |
| Preis | 286,00 € Zzgl. Versandkosten €40,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | PTPN6 / SHP1 (internal) |
| Gen-ID | 5777 |
| Immunogen | C-HTKNKREEKVKKQ |
| Format | Affinity-purified |
| Beschreibung | All names and symbols: PTPN6, SHP1 , protein tyrosine phosphatase, non-receptor type 6 , HCP, HCPH, HPTP1C, PTP-1C, SH-PTP1, SHP-1, SHP-1L, 70 kda SHP-1L protein, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, protein-tyrosine phosphatase 1C. Official Symbol: PTPN6. RefSeq number(s): NP_536858.1, NP_002822.2 |
| Spezifität | This antibody is expected to recognise both reported isoforms (NP_536858.1and NP_002822.2) Human |
Anwendungen
| Applikationshinweise | Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 70kDa band observed in lysates of cell lines Jurkat and U937 (calculated MW of 67.7kDa according to NP_536858.1 and 67.6kDa according to NP_002822.2). Recommended concentration: 0.2-0.5µg/ml. |
| Reinigung | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Lagerung | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Bilder
| ABIN190820 (0.2µg/ml) staining of Jurkat cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. |
Publikationen
| Publikationen |
Dubois, Bergeron, Kim et al.: "The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis." in: Nature medicine, Vol. 12, Issue 5, pp. 549-56, 2006 (PubMed).
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Alternativen
Alternativen zu Antigen "Protein-tyrosine Phosphatase 1C (PTPN6)", Typ "Antikörper" finden
| Wirte | Kaninchen (57), Maus (29), Ziege (10) |
| Reaktivitäten | Human (90), Maus (38), Ratte (Rattus) (36), Rind (Kuh) (15), Hund (3), Schwein (1) |
| Applikationen | Western Blot (WB) (68), Immunfluoreszenz (IF) (40), Durchflusszytometrie (FACS) (20), Immunhistochemie (IHC) (17), Enzyme Immunoassay (EIA) (16), ELISA (15), Immunpräzipitation (IP) (12), Immunhistochemie (Paraffinschnitte) (IHC (p)) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), Immunzytochemie (ICC) (6), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1) |
| Konjugate | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitope | pTyr536 (5), Center (3), internal (3), C-Term (2) |
