Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A) Antikörper

Antigen: Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A)

Synonyme: PR65A, MGC786, PR65, MGC95083, ppp2r1a, MGC53746, MGC76072, zgc:56296, wu:fa02h04, sis, ssv, c-sis, pdgf2, MGC89548, PPP2R1A, MGC128399, Ppp2r1a, DKFZp470L0914, RP-C, PP2Ac, PP2CA, PP2A, R75353, Pp2a1, PPP2CA

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN185382

Produktbeschreibung

Weitere Bezeichnung: PP2A / PPP2R1A

Gen-ID: 5518

Immunogen: C-KYFAQEALTVLSLA

Format: Affinity-purified

Beschreibung: All names and symbols: PPP2R1A, MGC786, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, PP2A, subunit A, R1-alpha isoform, PP2A, subunit A, PR65-alpha isoform, medium tumor antigen-associated 61 KDA protein, Serine/threonine protein phosphatase 2A, 65 KDA regulatory subunit A, alpha isoform. Official Symbol: PPP2R1A. RefSeq number(s): NP_055040.2. Gene ontology terms: RNA splicing, antigen binding, binding, ceramide metabolism, cytosol, inactivation of MAPK, induction of apoptosis, membrane, microtubule cytoskeleton, mitochondrion, negative regulation of cell growth, negative regulation of tyrosine phosphorylation of Stat3 protein, nucleus, phosphoprotein phosphatase activity, protein amino acid dephosphorylation, protein binding, protein complex assembly, protein heterodimerization activity, protein phosphatase type 2A activity, protein phosphatase type 2A complex, protein phosphatase type 2A regulator activity, regulation of DNA replication, regulation of Wnt receptor signaling pathway, regulation of cell adhesion, regulation of cell cycle, regulation of cell differentiation, regulation of growth, regulation of transcription, regulation of translation, response to organic substance, second-messenger-mediated signaling, soluble fraction

Spezifität: Human, Mouse, Rat, Dog 589 aa

Synonyme: PR65A, MGC786, PR65, MGC95083, ppp2r1a, MGC53746, MGC76072, zgc:56296, wu:fa02h04, sis, ssv, c-sis, pdgf2, MGC89548, PPP2R1A, MGC128399, Ppp2r1a, DKFZp470L0914, RP-C, PP2Ac, PP2CA, PP2A, R75353, Pp2a1, PPP2CA

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Approx 60kDa band observed in Human Thymus and Lymph Node lysates (calculated MW of 65.3kDa according to NP_055040.2). Recommended concentration: 0.03-0.1µg/ml.

Reinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Lagerung: Aliquot and store at -20°C. Minimize freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

ABIN185382 (0.03µg/ml) staining of Human Lymph Node lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publikationen

Publikationen: Hong, Sarge: "Regulation of protein phosphatase 2A activity by heat shock transcription factor 2." in: The Journal of biological chemistry, Vol. 274, Issue 19, pp. 12967-70, 1999 (PubMed).

Takakura, Kohno, Manda et al.: "Genetic alterations and expression of the protein phosphatase 1 genes in human cancers." in: International journal of oncology, Vol. 18, Issue 4, pp. 817-24, 2001 (PubMed).