PSMC5 Antikörper (C-Term)

Produktnummer ABIN183625

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PSMC5 in WB, IHC und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für PSMC5 Antikörper (C-Term) (ABIN183625)

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-PSMC5 Antikörper

Bindungsspezifität: C-Term

Sequenz: AEVKGVCTEA GMYALRERRV HVTQEDFEMA VAKVMQKDSE KNMSIKKLWK

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMC5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 406 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Andere Bezeichnung: PSMC5

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Alias Symbols: S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Protein Interaction Partner: HUWE1, KRT38, KRT40, PDCL, CIITA, FOS, THAP11, SUMO2, SUMO3, Gabbr2, PSMD14, UBE3C, UBC, PSMB4, RPS13, RPL29, PSMD12, PSMD11, PSMD8, PSMD3, PSMD1, PSMC6, DYNC1I2, ABCF1, KCMF1, UCHL5, KIAA0368, UBR4, ADRM1, MAP2, PARK2, FBXO6, RORA, PSMC4, BAG3, HIV2gp7,
Protein Size: 406

Molekulargewicht: 46 kDa

Gen-ID: 5705

NCBI Accession: NM_002805, NP_002796

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway