PSMC5 Antikörper (C-Term)

Produktnummer ABIN2780449

Produktdetails anti-PSMC5 Antikörper

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequenz: AEVKGVCTEA GMYALRERRV HVTQEDFEMA VAKVMQKDSE KNMSIKKLWK

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PSMC5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 406 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Andere Bezeichnung: PSMC5 (PSMC5 Produkte)

Synonyme: mSUG1 antikoerper, S8 antikoerper, SUG-1 antikoerper, SUG1 antikoerper, TBP10 antikoerper, TRIP1 antikoerper, p45 antikoerper, p45/SUG antikoerper, wu:fa14g03 antikoerper, wu:fb23a11 antikoerper, zgc:92464 antikoerper, sug-1 antikoerper, sug1 antikoerper, tbp10 antikoerper, Sug1 antikoerper, PSMC5 antikoerper, xsug1 antikoerper, protease (prosome, macropain) 26S subunit, ATPase 5 antikoerper, proteasome 26S subunit, ATPase 5 antikoerper, proteasome 26S subunit, ATPase 5 L homeolog antikoerper, proteasome 26S subunit, ATPase 5 S homeolog antikoerper, Psmc5 antikoerper, PSMC5 antikoerper, psmc5 antikoerper, psmc5.L antikoerper, psmc5.S antikoerper

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Alias Symbols: S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Protein Interaction Partner: HUWE1, KRT38, KRT40, PDCL, CIITA, FOS, THAP11, SUMO2, SUMO3, Gabbr2, PSMD14, UBE3C, UBC, PSMB4, RPS13, RPL29, PSMD12, PSMD11, PSMD8, PSMD3, PSMD1, PSMC6, DYNC1I2, ABCF1, KCMF1, UCHL5, KIAA0368, UBR4, ADRM1, MAP2, PARK2, FBXO6, RORA, PSMC4, BAG3, HIV2gp7,
Protein Size: 406

Molekulargewicht: 46 kDa

Gen-ID: 5705

NCBI Accession: NM_002805, NP_002796

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway