CD25 Antikörper

Produktnummer ABIN135175

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD25 in FACS, IP, IHC (fro), BR, Neut, Dep und CMCD. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD25 Antikörper (ABIN135175)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD25 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Neutralization (Neut), Depletion (Dep), Complement Mediated Cell Depletion (CMCD)

Klon: 7D4

Produktdetails anti-CD25 Antikörper

Verwendungszweck: Rat Anti-Mouse CD25-LE/AF

Spezifität: Mouse CD25, Mr 55 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD25 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, depletion, CMCD, and neutralization assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: IL-2 dependent BALB/c helper T cell clone HT2

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung: CD25

Hintergrund: The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus.

Gen-ID: 16184

UniProt: P01590

Pathways: JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation