BCL10 Antikörper (pSer138)

Produktnummer ABIN126733

Dieser Maus Monoklonal Antikörper detektiert spezifisch BCL10 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für BCL10 Antikörper (pSer138) (ABIN126733)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 6D3

Produktdetails anti-BCL10 Antikörper

Bindungsspezifität: pSer138

Spezifität: This antibody specifically recognizes bcl-10 phosphorylated at Serine 138 at 32 kDa in Western blot.

Produktmerkmale: Synonyms: BCL10, CIPER, CLAP, cCARMEN, mE10, c-E10, hCLAP, B-cell CLL/lymphoma 10, CED-3/ICH-1prodomain homologous E10-like regulator, CARD-containing molecule enhancingNF-kappa-B, Cellular homolog of vCARMEN, Mammalian CARD-containing adapter moleculeE10, Cellular-E10, CARD-like apoptotic protein

Aufreinigung: Subsequent Thiophilic Adsorption and Size Exclusion Chromatography.

Bestandteile: incl. positive Control

Immunogen: Phosphopeptide conjugated to KLH

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: BSA/Tween 20 based blocking and blot incubation buffer. Included Positive Control: Cell lysate from serum starved SW480 cells (please see: 'Protocols').
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Protokoll: Positive Control Cell Lysate: SW 480 Untreated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL water (15 min, RT).

Buffer: 1 mL2 x PBS / 0.09 % Sodium Azide / PEG and Sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Andere Bezeichnung: Bcl-10

Hintergrund: Bcl-10 is an apoptosis-inducing molecule interacting with caspase 9. Bcl-10 enhances pro-caspase 9 processing and induces apoptosis through caspase 9 activation.Synonyms: B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10

Gen-ID: 8915

UniProt: O95999

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine