Erythroid beta Spectrin Antikörper

Antigen: Erythroid beta Spectrin

Klonalität: Monoklonal (DB2)

Wirt: Maus

Reaktivität: Human

Applikation: Immunpräzipitation (IP), Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN108438

Produktbeschreibung

Immunogen: Monoclonal antibody to erythroid b-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Ghost proteins of human red blood cells were used as immunogen

Format: Purified

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: DB2

Beschreibung: Monoclonal Antibody to Human Spectrins

Spezifität: The antibody is specific to the 220kD human erythroid b-spectrin. The protein is also present in the membranes of human skeletal muscle cells

Anwendungen

Applikationshinweise: Various immunochemical reactions to detect erythroid spectrins. Identification of erythroid leukemias. Can be used also to monitor the integrity of muscle cell plasma membranes. Works in immunoprecipitation, western blotting and immunocytochemistry. No re

Lagerung: This product should be stored at +2 C to +8 C

Forschungsgebiet: Zytoskelett

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blotting polypeptides of ghosts of human erythrocytes (Lane 1, total protein profile) and reaction with MAb AF10 (Erythroid a-Spectrin)(Lane 2) and MAb DB2 (Erythroid b-Spectrin)

Publikationen

Publikationen: Tani T, Ylanne J, Virtanen I: "Expression of megakaryocytic and erythroid properties in human leukemic cells." in: Exp Hematol, Vol. 24, Issue 2, pp. 158-68, 1996 (PubMed).

Auranen M, Rapola J, Pihko H et al.: "Muscle membrane-skeleton protein changes and histopathological characterization of muscle-eye-brain disease." in: Neuromuscul Disord, Vol. 10, Issue 1, pp. 16-23, 2000 (PubMed).