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Sclerostin (SOST) ELISA Kits

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Zusätzlich bieten wir Ihnen Sclerostin Antikörper (96) und Sclerostin Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
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Top Sclerostin ELISA Kits auf antikoerper-online.de

Showing 10 out of 41 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
874,71 €
Details
Maus 10pg/mL 15.6-1000 pg/mL Mouse Sclerostin/SOST PicoKine ELISA Kit standard curve 96 Tests Anmelden zum Anzeigen 8 bis 11 Tage
507,05 €
Details
Ratte 32 pg/mL 78-5.000 pg/mL 96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
804,23 €
Details
Rind (Kuh) 15.63 pg/mL 4000-62.5 pg/mL   96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
874,71 €
Details
Maus 6.19 pg/mL 156.25-10000 pg/mL   96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
914,29 €
Details
Ratte 4.86 pg/mL 156.25-10000 pg/mL   96 Tests Anmelden zum Anzeigen 7 bis 10 Tage
965,08 €
Details
Meerschweinchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
673,47 €
Details
Kaninchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
673,47 €
Details
Affe 0.1 ng/mL 1.0-25 ng/mL   96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
673,47 €
Details
Hund 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 9 bis 12 Tage
673,47 €
Details

Am meisten referenzierte Sclerostin ELISA Kits

  1. Human Sclerostin ELISA Kit für Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. in Gynecologic and obstetric investigation 2013 (PubMed)
    Zeige alle 5 Referenzen für ABIN457071

  2. Rat (Rattus) Sclerostin ELISA Kit für Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. in Life sciences 2013 (PubMed)
    Zeige alle 2 Referenzen für ABIN416496

  3. Mouse (Murine) Sclerostin ELISA Kit für Sandwich ELISA - ABIN1889353 : Brunkow, Gardner, Van Ness, Paeper, Kovacevich, Proll, Skonier, Zhao, Sabo, Fu, Alisch, Gillett, Colbert, Tacconi, Galas, Hamersma, Beighton, Mulligan: Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. in American journal of human genetics 2001 (PubMed)
    Zeige alle 2 Referenzen für ABIN1889353

Weitere ELISA Kits für Sclerostin Interaktionspartner

Human Sclerostin (SOST) Interaktionspartner

  1. chronic TNFalpha (tumor necrosis factor alpha (zeige TNF ELISA Kits))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  2. Sclerostin levels are elevated in CKD patients and are associated with inflammation, vascular lesions, uremia and (potentially) mortality.

  3. Our data also demonstrated that vitamin D deficient newborns exhibited lower sclerostin levels than vitamin D sufficient newborns.

  4. the first evidence suggesting that LRP4 (zeige LRP4 ELISA Kits) is responsible for the retention of sclerostin in the bone environment in humans.

  5. higher serum sclerostin levels are associated with higher bone mineral density, lower aortic calcification scores, and a better survival rate in hemodialysis patients

  6. findings suggest that serum TGF-beta1 (zeige TGFB1 ELISA Kits) level increases during postmenopause and declines in old age. Sclerostin production is inhibited by TGF-beta1 (zeige TGFB1 ELISA Kits) during early postmenopause

  7. a cell model of human dermal fibroblasts in order to investigate the functions of sclerostin, is reported.

  8. The aims of this study were to evaluate OCN and sclerostin levels in subjects who underwent coronary artery bypass graft (CABG) surgery compared with those in normal controls.

  9. two affected siblings who carried a novel nonsense mutation of SOST in a consanguineous family from China, is reported.

  10. Sclerostin serum levels are not associated with an adverse metabolic profile during pregnancy in women with GDM and PE

Mouse (Murine) Sclerostin (SOST) Interaktionspartner

  1. chronic TNFalpha (tumor necrosis factor alpha (zeige TNF ELISA Kits))-dependent arthritis, fibroblast-like synoviocytes constitute a major source of sclerostin and that either the lack of sclerostin or its antibody-mediated inhibition leads to an acceleration of rheumatoid arthritis (RA)-like disease.

  2. Data show that the phenotype of Notch (zeige NOTCH1 ELISA Kits) activation in osteocytes was prevented in matrix protein 1 (Dmp1 (zeige DMP1 ELISA Kits))-Cre;Rosa(Notch (zeige NOTCH1 ELISA Kits)) mice hemizygous for the Dmp1 (zeige DMP1 ELISA Kits)-sclerostin (SOST) transgene.

  3. Results found that sclerostin enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (zeige TAZ ELISA Kits)-responsive transcriptional activity and TAZ (zeige TAZ ELISA Kits)-responsive gene expression, indicating a role for TAZ (zeige TAZ ELISA Kits) as a regulator of adipogenesis by sclerostin.

  4. Our results suggested that sclerostin could be expressed in the liver and sustained successfully at high levels in the blood by using the PhiC31 integrase system, leading to trabecular bone loss.

  5. Sclerostin depletion enhances tibial fracture healing.

  6. SOST gene is involved in the regulation of renal interstitial fibrosis (RIF) progression. In obstructive kidney injury, SOST gene deletion would probably enhance renal fibrogenic response and promote the progression of RIF.

  7. Data (including data from studies in knockout/transgenic mice) suggest that Lrp6 (lipoprotein receptor-related protein 6 (zeige LRP6 ELISA Kits)) is required for suppression of Sost expression by parathyroid hormone (zeige PTH ELISA Kits) (here, human PTH (zeige PTH ELISA Kits) peptide 1-34).

  8. These in vivo data support in vitro studies regarding the mechanism of HBM (zeige LRP5 ELISA Kits)-causing mutations, and imply that HBM LRP5 (zeige LRP5 ELISA Kits) receptors differ in their relative sensitivity to inhibition by SOST and DKK1 (zeige DKK1 ELISA Kits).

  9. These findings indicated that AMPK (zeige PRKAA1 ELISA Kits) regulated RANKL (zeige TNFSF11 ELISA Kits) and sclerostin expression through the mevalonate pathway in osteocytes.

  10. Sclerostin inhibits bone formation through Lrp5 (zeige LRP5 ELISA Kits) interaction.

Sclerostin (SOST) Antigen-Profil

Beschreibung des Gens

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Genbezeichner und Symbole assoziert mit Sclerostin (SOST) ELISA Kits

  • sclerostin (LOC100313724) Antikörper
  • sclerostin (SOST) Antikörper
  • sclerostin (Sost) Antikörper
  • sclerostin-like (LOC100513306) Antikörper
  • 5430411E23Rik Antikörper
  • CDD Antikörper
  • LOC100313724 Antikörper
  • VBCH Antikörper

Bezeichner auf Proteinebene für Sclerostin (SOST) ELISA Kits

sclerostin , sclerosteosis

GENE ID SPEZIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
Ausgewählte Anbieter für Sclerostin (SOST) ELISA Kits
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