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Sclerostin ELISA Kit

SOST Reaktivität: Human AA 24-213 Colorimetric Sandwich ELISA
Produktnummer ABIN5510605
  • Target Alle Sclerostin (SOST) ELISA Kits anzeigen
    Sclerostin (SOST)
    Bindungsspezifität
    AA 24-213
    Reaktivität
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Nachweismethode
    Colorimetric
    Methodentyp
    Sandwich ELISA
    Applikation
    ELISA
    Verwendungszweck
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
    Marke
    PicoKine™
    Analytische Methode
    Quantitative
    Spezifität
    Expression system for standard: NSO, Immunogen sequence: Q24-Y213
    Kreuzreaktivität (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Produktmerkmale

    Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .

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  • Plattentyp
    Pre-coated
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Haltbarkeit
    12 months
  • Target Alle Sclerostin (SOST) ELISA Kits anzeigen
    Sclerostin (SOST)
    Andere Bezeichnung
    SOST (SOST Produkte)
    Synonyme
    LOC100313724 ELISA Kit, CDD ELISA Kit, VBCH ELISA Kit, 5430411E23Rik ELISA Kit, sclerostin ELISA Kit, LOC100313724 ELISA Kit, SOST ELISA Kit, Sost ELISA Kit
    Hintergrund

    Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .

    Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.

    Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,

    Full Gene Name: Sclerostin

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    Q9BQB4
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