anti-SMAD2 Antikörper

Protein Überblick

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with SMAD2

• SMAD family member 2 (SMAD2) Antikörper
• SMAD family member 2-Z (SMAD2Z) Antikörper
• SMAD family member 2 (smad2) Antikörper
• SMAD family member 2 S homeolog (smad2.S) Antikörper
• SMAD family member 2 (Smad2) Antikörper

• 7120426M23Rik Antikörper
• fj43c06 Antikörper
• hmad-2 Antikörper
• hsmad2 Antikörper
• jv18 Antikörper
• Alle Synonyme
• jv18-1 Antikörper
• Madh2 Antikörper
• MAD homolog 2 Antikörper
• Madr2 Antikörper
• mMad2 Antikörper
• Mothers against DPP homolog 2 Antikörper
• Smad-2 Antikörper
• SMAD 2 Antikörper
• Smad2 Antikörper
• wu:fj43c06 Antikörper
• Xmad2 Antikörper
• XSmad2 Antikörper

Bezeichner auf Proteinebene für SMAD2

MAD homolog 2 , SMAD, mothers against DPP homolog 2 , Sma- and Mad-related protein 2 , mother against DPP homolog 2 , mothers against decapentaplegic homolog 2 , SMAD 2 , mothers against DPP homolog 2 , mothers against decapentaplegic-like 2 , MAD (mothers against decapentaplegic, Drosophila) homolog 2 , SMA- and MAD-related protein 2 , SMAD family member 2 , Smad 2 , mad-related protein 2 , LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2