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Human PGF Protein expressed in Escherichia coli (E. coli) - ABIN413725
Ding, Huang, Song, Gao, Yuan, Wang, Cai, Fu, Luo: NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha. in Journal of immunology (Baltimore, Md. : 1950) 2010
Rat (Rattus) PGF Protein expressed in Escherichia coli (E. coli) - ABIN2126310
Zhang, Zhao, Yuan, Wu, Jiang, Luo, Zhao: Knockdown of placental growth factor (PLGF) mitigates hyperoxia-induced acute lung injury in neonatal rats: Suppressive effects on NFκB signaling pathway. in International immunopharmacology 2016
PlGF level showed an inversely proportional effect on the foetal weight.
these data suggest that PlGF may increase non-small cell lung cancer metastasis through SRp40 (zeige SRSF5 Proteine)-mediated mRNA splicing of VEGF (zeige VEGFA Proteine).
The present study investigated the interplay of VEGF (zeige VEGFA Proteine)-A165a isoform, the anti-angiogenic VEGF (zeige VEGFA Proteine)-A165b, placental growth factor (PIGF) and their receptors, VEGFR1 (zeige FLT1 Proteine) and VEGFR2 (zeige KDR Proteine), on junctional occupancy of VE-cadherin (zeige CDH5 Proteine) and macromolecular leakage in human endothelial monolayers and the perfused placental microvascular bed.
PIGF (zeige PIGF Proteine) enhances TLR-signaling upstream of IKK (zeige CHUK Proteine) and contributes to an exaggerated pathologic pro-inflammatory state in response to activation of maternal and fetal mononuclear phagocytes by specific TLR agonists
Lower PIGF (zeige PIGF Proteine) and higher PAPP-A (zeige PAPPA Proteine) and free beta-hCG (zeige CGA Proteine) levels were found in the fetal circulation of near-term severe preeclamptic pregnancies
The early variations of PIGF (zeige PIGF Proteine) and soluble fms-like tyrosine kinase-1 (zeige FLT1 Proteine) concentrations in newly pregnant obstetric antiphospholipid syndrome (oAPS) may help to detect patients at low risk of placenta-mediated complications (PMC).
There is a significant negative correlation between the concentration of sFLt-1 and PIGF (zeige PIGF Proteine) in normal pregnancy.
knockdown of PIGF (zeige PIGF Proteine) in spheroid body cells derived from two gastric cancer cell lines reduced in vitro tumorigenicity and stemness properties of spheroid body cells such as self-renewal ability, colony forming, migratory, and MMPs activities and decreased ability to differentiation and angiogenesis
Data showed that sFlt-1/PIGF (zeige PIGF Proteine) ratio increases with volume overload and persistent hypoxia after surgery with CHD (zeige CHDH Proteine).
Glioma cell-released PIGF (zeige PIGF Proteine) can induce Bregs to suppress CD8 (zeige CD8A Proteine)(+) T cell activities.
Data indicate that VEGF-B (zeige VEGFB Proteine) is a high-affinity VEGFR-1 (zeige FLT1 Proteine) ligand that, unlike PIGF (zeige PIGF Proteine), cannot efficiently induce signaling downstream of VEGFR-1 (zeige FLT1 Proteine).
the lack of PIGF (zeige PIGF Proteine) may have contributed to the delayed angiogenic response and the prothrombotic phenotype observed in the PIGF (zeige PIGF Proteine)(-/-)animals.
Overexpression of VEGF (zeige VEGFA Proteine) but not PIGF (zeige PIGF Proteine) exacerbated the lipopolysaccharide-mediated toxic effects, supporting a pathophysiological role for VEGF (zeige VEGFA Proteine) in mediating the sepsis phenotype.
Findings indicate that placental growth factor (PlGF) plays an important role in liver fibrosis-associated angiogenesis and that blockage of PlGF could be an effective strategy for chronic liver disease.
Data demonstrate that PlGF is expressed in vivo and that its expression is restricted to the areas of the tumors where the highest levels of hypoxia occur. Also, hypoxia activates PlGF expression in cultured lymphatic endothelial cells.
Study provides mechanistic and clinical evidence that decreased PLGF levels in the placenta after in utero alcohol exposure are associated to brain angiogenesis defects. Measurement of PLGF levels at birth in the placenta or the fetal blood may serve as a predictive marker for subsequent neurodevelopmental outcomes of exposed fetuses.
PGF (zeige PTGFR Proteine) deficiency is associated with impaired cerebral vascular development in mice.
PlGF inhibition attenuates PERK (zeige EIF2AK3 Proteine) activation, likely by tempering hypoxia in HCC (zeige FAM126A Proteine) via vessel normalisation. The UPR is able to regulate PlGF expression, suggesting the existence of a feedback mechanism for hypoxia-mediated UPR
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13 (zeige IL13 Proteine).
Data indicate that placental growth factor (PlGF) is needed in the spleen to allow the activation of T cells and blood pressure raising.
Study reports polymorphisms in the bovine PGF gene significantly associated with the maternal effect on stillbirth and calving ease in animals under selection.
placenta growth factor expression is regulated by both VEGF (zeige VEGFA Proteine) and hyperglycaemia via VEGFR-2 (zeige KDR Proteine)
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.
placenta growth factor
, placental growth factor, vascular endothelial growth factor-related protein
, placenta growth factor-like