UNC13D Produkte
(Unc-13 Homolog D (UNC13D))
Kategorien
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008].
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Ausgewählte UNC13D Kategorien
UNC13D Antikörper
High quality antibodies with extensive validation data.
UNC13D Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UNC13D Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
Kat. Nr.
ABIN531286
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (3)
Kat. Nr.
ABIN2856569
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN185677
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene UNC13D ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6219996
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UNC13D Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324647
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3096260
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2735014
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UNC13D Produkten
: "A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4." in: The Journal of cell biology, Vol. 217, Issue 8, pp. 2877-2890, (2018) (PubMed).: "Munc13-4 functions as a Ca(2+) sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles." in: Molecular biology of the cell, Vol. 28, Issue 6, pp. 792-808, (2017) (PubMed).
: "Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis." in: eLife, Vol. 4, (2016) (PubMed).
: "Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A." in: Human mutation, Vol. 27, Issue 1, pp. 62-8, (2005) (PubMed).
: "Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)." in: Cell, Vol. 115, Issue 4, pp. 461-73, (2003) (PubMed).
Synonyme und alternative Namen zu UNC13D
unc-13 homolog D (UNC13D), unc-13 homolog D (C. elegans) (Unc13d), unc-13 homolog D (Unc13d), transforming growth factor beta induced (TGFBI), unc-13 homolog D (unc13d), unc-13 homolog D (un13d), 2610108D09Rik, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, FHL3, HLH3, HPLH3, Jinx, LCD1, mFLJ00067, Munc13-4, UNC13D, Unc13h4Bezeichner auf Proteinebene für UNC13D
- protein unc-13 homolog D
- unc-13 homolog D (C. elegans)
- likely ortholog of H. sapiens unc-13 homolog D (UNC13D)
- RGD-CAP
- RGD-containing collagen-associated protein
- beta ig-h3
- kerato-epithelin
- transforming growth factor-beta-induced protein ig-h3
- protein unc-13 homolog D-like
- unc-13 homolog D
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