UGT1A1 Produkte
(UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
Kategorien
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008].
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Ausgewählte UGT1A1 Kategorien
UGT1A1 Antikörper
High quality antibodies with extensive validation data.
UGT1A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
UGT1A1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene UGT1A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN6149895
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IF
Validierungen
- (4)
Kat. Nr.
ABIN7262012
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (5)
Kat. Nr.
ABIN5693290
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene UGT1A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960358
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6975305
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6960359
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene UGT1A1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324569
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3113166
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408798
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren UGT1A1 Produkten
: "A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin." in: Journal of medicinal chemistry, Vol. 60, Issue 23, pp. 9664-9675, (2017) (PubMed).: "Phenethyl isothiocyanate and indole-3-carbinol from cruciferous vegetables, but not furanocoumarins from apiaceous vegetables, reduced PhIP-induced DNA adducts in Wistar rats." in: Molecular nutrition & food research, Vol. 60, Issue 9, pp. 1956-66, (2016) (PubMed).
: "Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats." in: The Journal of nutrition, Vol. 145, Issue 3, pp. 442-51, (2015) (PubMed).
: "Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 58-63, (2015) (PubMed).
: "Danning tablets attenuates ?-naphthylisothiocyanate-induced cholestasis by modulating the expression of transporters and metabolic enzymes." in: BMC complementary and alternative medicine, Vol. 14, pp. 249, (2014) (PubMed).
Synonyme und alternative Namen zu UGT1A1
UDP glucuronosyltransferase family 1 member A1 (UGT1A1), UDP glucuronosyltransferase 1 family, polypeptide A1 (Ugt1a1), UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1), UDP-glucuronosyltransferase 1-1 (LOC100065342), UDP-glucuronosyltransferase (LOC100125517), UDP-glucuronosyltransferase 1-1 (LOC100229734), UDP-glucuronosyltransferase 1-6 (LOC100405984), UDP-glucuronosyltransferase 1-1 (LOC100511479), UDP glucuronosyltransferase family 1 member A1 (Ugt1a1), UDP glucuronosyltransferase 1 family polypeptide a1 (ugt1a1), BILIQTL1, GNT1, Gnt1, HUG-BR1, UDPGT, Udpgt, Udpgt-1a, UDPGT 1-1, UGT1, Ugt1, UGT1A, UGT1A01, UgtBr1, zgc:123097Bezeichner auf Proteinebene für UGT1A1
- UDP glycosyltransferase 1 family, polypeptide A1
- UDP-glucuronosyltransferase 1-1
- UDP-glucuronosyltransferase 1-A
- UDP-glucuronosyltransferase 1A1
- UGT-1A
- UGT1*1
- UGT1-01
- UGT1.1
- bilirubin UDP-glucuronosyltransferase 1-1
- bilirubin UDP-glucuronosyltransferase isozyme 1
- bilirubin-specific UDPGT isozyme 1
- UDP-glucuronosyltransferase 1 family, member 1
- UDP-glucuronosyltransferase 1 family, polypeptide A1
- UDPGT
- UDP glucuronosyltransferase 1 family, polypeptide A1
- uridine diphosphate glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase UGT1A01
- UDP glucuronosyltransferase 1 family polypeptide A1
- UDP glycosyl transferase 1A1
- UDP-glucuronosyltransferase 1-1-like
- B1
- UDP-glucuronosyltransferase 1 family member 1
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