Protein Überblick

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

Alternative names and synonyms associated with Aconitase 1 (ACO1)

• aconitase 1 (ACO1) Antikörper
• aconitase 1 (Aco1) Antikörper

• Aco-1 Antikörper
• Acon1 Antikörper
• ACONS Antikörper
• AI256519 Antikörper
• IREB1 Antikörper
• Alle Synonyme
• Irebp Antikörper
• IREBP1 Antikörper
• Irp1 Antikörper
• Ratireb Antikörper

Bezeichner auf Proteinebene für Aconitase 1 (ACO1) ELISA Kits

IRE-BP 1 , aconitate hydratase, cytoplasmic , citrate hydro-lyase , cytoplasmic aconitate hydratase , ferritin repressor protein , iron regulatory protein 1 , iron-responsive element binding protein 1 , iron-responsive element-binding protein 1 , IRP1 , cytoplasmic aconitase