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TPR Produkte

(Nucleoprotein TPR (TPR))

Kategorien

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008].

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Ausgewählte TPR Kategorien

TPR Antikörper

High quality antibodies with extensive validation data.

Empfohlene TPR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN563243
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (2)
Kat. Nr. ABIN521068
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit
Applikation WB
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6746941
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TPR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323452
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TPR Produkten

Wu, Zhou, Oshiro-Rapley, Li, Paulo, Webster, Mou, Kacergis, Talkowski, Carr, Gygi, Zheng, Soukas: "An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer." in: Cell, Vol. 167, Issue 7, pp. 1705-1718.e13, (2017) (PubMed).

Huang, Chiu, Liao, Chuang, Shih, Liu: "Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways." in: PLoS ONE, Vol. 10, Issue 8, pp. e0133699, (2015) (PubMed).

Schweizer, Ferrás, Kern, Logarinho, Cheeseman, Maiato: "Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis." in: The Journal of cell biology, Vol. 203, Issue 6, pp. 883-93, (2014) (PubMed).

Ogawa, Miyamoto, Oka, Yoneda: "The interaction between importin-α and Nup153 promotes importin-α/β-mediated nuclear import." in: Traffic (Copenhagen, Denmark), Vol. 13, Issue 7, pp. 934-46, (2012) (PubMed).

Copeland, Newcomb, Brown: "Herpes simplex virus replication: roles of viral proteins and nucleoporins in capsid-nucleus attachment." in: Journal of virology, Vol. 83, Issue 4, pp. 1660-8, (2009) (PubMed).

Chan, Qian, Diamond, Liu, Gritsenko, Monroe, Camp, Smith, Katze: "Quantitative analysis of human immunodeficiency virus type 1-infected CD4+ cell proteome: dysregulated cell cycle progression and nuclear transport coincide with robust virus production." in: Journal of virology, Vol. 81, Issue 14, pp. 7571-83, (2007) (PubMed).

Tominaga, Morisaki, Kaneko, Fujimoto, Tanaka, Ohtsubo, Hirai, Okayama, Ikeda, Nakanishi: "Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53." in: The Journal of biological chemistry, Vol. 274, Issue 44, pp. 31463-7, (1999) (PubMed).

Synonyme und alternative Namen zu TPR

translocated promoter region, nuclear basket protein (TPR), nuclear pore anchor (NUA), translocated promoter region, nuclear basket protein (Tpr), 2610029M07Rik, AtTPR, C77892, nuclear pore anchor, TRANSLOCATED PROMOTER REGION, YUP8H12R.12, YUP8H12R_12

Bezeichner auf Proteinebene für TPR

  • translocated promoter region (to activated MET oncogene)
  • NPC-associated intranuclear protein
  • nuclear pore complex-associated protein Tpr
  • nucleoprotein TPR
  • translocated promoter region and nuclear basket protein
  • megator
  • nuclear pore complex-associated protein TPR
  • translocated promoter region protein
  • tumor potentiating region
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