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TPCN2 Produkte

(Two Pore Segment Channel 2 (TPCN2))
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009].

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Ausgewählte TPCN2 Kategorien

TPCN2 Antikörper

High quality antibodies with extensive validation data.

TPCN2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TPCN2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TPCN2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC, WB
Validierungen
  • (22)
Kat. Nr. ABIN351017
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN351015
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IF, IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN7043872
Menge 25 μL
Datenblatt Datenblatt

Empfohlene TPCN2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN6199931
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN6199932
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TPCN2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3074787
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3125363
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3116758
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TPCN2 Produkten

Lin, Izar, Wang, Yapp, Mei, Shah, Santagata, Sorger: "Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes." in: eLife, Vol. 7, (2019) (PubMed).

Lee, Tong, Cheng, Hung, Cheung: "Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology." in: Scientific reports, Vol. 6, pp. 20282, (2016) (PubMed).

Favia, Desideri, Gambara, DAlessio, Ruas, Esposito, Del Bufalo, Parrington, Ziparo, Palombi, Galione, Filippini: "VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 44, pp. E4706-15, (2014) (PubMed).

Arndt, Castonguay, Arlt, Meyer, Hassan, Borth, Zierler, Wennemuth, Breit, Biel, Wahl-Schott, Gudermann, Klugbauer, Boekhoff: "NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa." in: Molecular biology of the cell, Vol. 25, Issue 6, pp. 948-64, (2014) (PubMed).

Calcraft, Ruas, Pan, Cheng, Arredouani, Hao, Tang, Rietdorf, Teboul, Chuang, Lin, Xiao, Wang, Zhu, Lin, Wyatt, Parrington, Ma, Evans, Galione, Zhu: "NAADP mobilizes calcium from acidic organelles through two-pore channels." in: Nature, Vol. 459, Issue 7246, pp. 596-600, (2009) (PubMed).

Synonyme und alternative Namen zu TPCN2

two pore segment channel 2 (tpcn2), two pore segment channel 2 (Tpcn2), two pore segment channel 2 (TPCN2), two pore segment channel 2 L homeolog (tpcn2.L), two pore calcium channel protein 2 (LOC100444397), BC025890, D830047E22Rik, fi42c05, im:7140344, MGC115225, SHEP10, TPC2, wu:fi42c05, zgc:152898

Bezeichner auf Proteinebene für TPCN2

  • two pore calcium channel protein 2
  • voltage-dependent calcium channel protein TPC2
  • two pore segment channel 2
  • two pore calcium channel protein 2-like
  • two-pore calcium channel protein 2
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