TNF alpha Proteine
(Tumor Necrosis Factor alpha (TNF alpha))
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008].
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TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
custom-made
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
TNF alpha
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
HPLC verified
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
3 Referenzen
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by reduced SDS-PAGE.
Active
2 Referenzen
TNF alpha
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
3 Referenzen
TNF alpha
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
TNF alpha
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE
Active
TNF alpha
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
3 Referenzen
TNF alpha
Spezies: Human
Wirt: Yeast (Pichia pastoris)
> 97 % by SDS-PAGE.
Active
2 Referenzen
TNF alpha
Spezies: Schwein
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
TNF alpha
Spezies: Meerschweinchen
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
TNF alpha
Spezies: Hund
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
TNF alpha
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
1 image
TNF alpha
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
1 image
TNF alpha
Spezies: Maus
Wirt: Yeast (Pichia pastoris)
Recombinant
> 95 % as analyzed by reducing SDS-PAGE.
Active
1 reference
TNF alpha
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 % by SDS - PAGE
SDS
Active
1 image
TNF alpha
Spezies: Maus
Wirt: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
Active
1 image
Aktuelle Publikationen für unsere TNF alpha Proteine
: "Dual-optofluidic waveguide in-line fiber biosensor for real-time label-free detection of interferon-gamma with temperature compensation." in: Optics express, Vol. 28, Issue 7, pp. 10491-10504, (2021) (PubMed).: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Sex Differences in Rat Intervertebral Disc Structure and Function Following Annular Puncture Injury." in: Spine, Vol. 44, Issue 18, pp. 1257-1269, (2020) (PubMed).
: "Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients." in: Experimental & molecular medicine, Vol. 52, Issue 4, pp. 629-642, (2020) (PubMed).
: "Decrease of MiR-31 induced by TNF-α inhibitor activates SATB2/RUNX2 pathway and promotes osteogenic differentiation in ethanol-induced osteonecrosis." in: Journal of cellular physiology, Vol. 234, Issue 4, pp. 4314-4326, (2019) (PubMed).
: "Overexpression of microRNA-590-3p promotes the proliferation of and inhibits the apoptosis of myocardial cells through inhibition of the NF-κB signaling pathway by binding to RIPK1." in: Journal of cellular biochemistry, Vol. 120, Issue 3, pp. 3559-3573, (2019) (PubMed).
: "MAbTope: A Method for Improved Epitope Mapping." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 10, pp. 3096-3105, (2019) (PubMed).
: "Glutaminase C Regulates Microglial Activation and Pro-inflammatory Exosome Release: Relevance to the Pathogenesis of Alzheimer's Disease." in: Frontiers in cellular neuroscience, Vol. 13, pp. 264, (2019) (PubMed).
: "The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway." in: Journal of cellular biochemistry, Vol. 119, Issue 2, pp. 1979-1991, (2018) (PubMed).
: "Surrogate potency assays: Comparison of binding profiles complements dose response curves for unambiguous assessment of relative potencies." in: Journal of pharmaceutical analysis, Vol. 8, Issue 2, pp. 138-146, (2018) (PubMed).
Aliase für TNF alpha Proteine
tumor necrosis factor (TNF) Proteinetumor necrosis factor (Tnf) Proteine
tumor necrosis factor (tnf) Proteine
tumor necrosis factor b (TNF superfamily, member 2) (tnfb) Proteine
tumor necrosis factor alpha (tnf-alpha) Proteine
tumor necrosis factor (LOC103694380) Proteine
tumor necrosis factor a (TNF superfamily, member 2) (tnfa) Proteine
Cachectin Proteine
cTNF Proteine
DIF Proteine
dif Proteine
RATTNF Proteine
tnf Proteine
TNF-a Proteine
TNF-alpha Proteine
Tnf-alpha Proteine
TNF-ALPHA Proteine
tnf-alpha Proteine
TNFA Proteine
Tnfa Proteine
TNFa Proteine
tnfa Proteine
tnfa-like Proteine
TNFalpha Proteine
Tnfsf1a Proteine
TNFSF2 Proteine
tnfsf2 Proteine
xtnf Proteine
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