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TGS1 Proteine

(Trimethylguanosine Synthase 1 (TGS1))

Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation (By similarity).

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TGS1 Protein (AA 1-853) (His tag)

custom-made TGS1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Tgs1 Protein, UniprotID Q923W1

3 Abbildungen

Produktnummer ABIN7564859

Details

TGS1 Protein (AA 1-853) (His tag)

custom-made TGS1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant TGS1 Protein, UniprotID Q96RS0

3 Abbildungen

Produktnummer ABIN7555781

Details

TGS1 Protein (AA 713-853) (His-IF2DI Tag)

TGS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for Trimethylguanosine Synthase 1 (TGS1) (AA 713-853) protein (His-IF2DI Tag) (ABIN7124691)

1 image

Produktnummer ABIN7124691

Details

TGS1 Protein (AA 1-141) (GST tag)

TGS1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Trimethylguanosine Synthase 1 (TGS1) (AA 1-141) protein (GST tag) (ABIN1322650)

1 image

Produktnummer ABIN1322650

Details

TGS1 Protein (AA 1-853) (GST tag)

TGS1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (GST tag) (ABIN1322652)

1 image

Produktnummer ABIN1322652

Details

TGS1 Protein (AA 1-853) (Strep Tag)

custom-made TGS1 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Produktnummer ABIN3136894

Details

TGS1 Protein (AA 1-853) (Strep Tag)

custom-made TGS1 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Produktnummer ABIN3095924