TGS1 Protein (AA 713-853, partial) (His-SUMO Tag)
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- Target Alle TGS1 Proteine anzeigen
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 713-853, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses TGS1 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product TGS1 Protein
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Trimethylguanosine Synthase 1 (TGS1) (AA 1-141) protein (GST tag)
TGS1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (GST tag)TGS1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (Strep Tag)Crystallography grade TGS1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Trimethylguanosine Synthase 1 (TGS1) (AA 1-853) protein (Strep Tag)Crystallography grade TGS1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- TGS1 (Trimethylguanosine Synthase 1 (TGS1))
- Andere Bezeichnung
- TGS1 (TGS1 Produkte)
- Synonyme
- NCOA6IP Protein, PIMT Protein, PIPMT Protein, D4Ertd800e Protein, Ncoa6ip Protein, Pimt Protein, trimethylguanosine synthase 1 Protein, trimethylguanosine synthase 1 L homeolog Protein, TGS1 Protein, Tgs1 Protein, tgs1.L Protein
- Hintergrund
- Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
- Molekulargewicht
- 31.64 kDa
- UniProt
- Q96RS0
- Pathways
- Mitotic G1-G1/S Phases, Regulation of Lipid Metabolism by PPARalpha, Ribonucleoprotein Complex Subunit Organization
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