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TGF-beta Produkte

(TGF-beta (TGFb))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].

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Ausgewählte TGF-beta Kategorien

TGF-beta Antikörper

High quality antibodies with extensive validation data.

TGF-beta ELISA Kits

Reliable ELISA kits for a wide range of species.

TGF-beta Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TGF-beta Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rabbit, Rat, Sheep
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN707021
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mammalian, Mouse, Rabbit, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN2476753
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Cow, Dog, Hamster, Human, Monkey, Mouse, Rat
Applikation ELISA, Func, D, ELISA (Capture)
Validierungen
  • (1)
Kat. Nr. ABIN6940723
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TGF-beta ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Monkey
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1059453
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Sheep
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1059454
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Chicken
Analytical Method Competition ELISA
Validierungen
Kat. Nr. ABIN1059452
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TGF-beta Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Hi-5 Cells
Validierungen
Kat. Nr. ABIN2469123
Menge 0.002 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TGF-beta Produkten

Baumeier, Escher, Aleshcheva, Pietsch, Schultheiss: "Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy." in: Basic research in cardiology, Vol. 116, Issue 1, pp. 1, (2021) (PubMed).

Playford, Cattell, Marchbank: "Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials." in: PLoS ONE, Vol. 15, Issue 6, pp. e0234719, (2020) (PubMed).

Sunil Gowda, Rajasowmiya, Vadivel, Banu Devi, Celestin Jerald, Marimuthu, Devipriya: "Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 52, pp. 170-177, (2018) (PubMed).

Xia, Ren, Zhu, Yu, Zhang, Sun, Zhao, Chen: "Downregulation of miR-145 in venous malformations: Its association with disorganized vessels and sclerotherapy." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 100, pp. 126-131, (2017) (PubMed).

Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." in: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

Polichnowski, Lan, Geng, Griffin, Venkatachalam, Bidani: "Severe renal mass reduction impairs recovery and promotes fibrosis after AKI." in: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 7, pp. 1496-507, (2014) (PubMed).

Bob, Gluhovschi, Herman, Petrica, Bozdog, Gluhovschi, Velciov, Gadalean, Timar, Potencz, Dema, Schiller: "Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis." in: Renal failure, Vol. 36, Issue 8, pp. 1208-14, (2014) (PubMed).

Moore, Sawyer, Charokopos, Skokos, Kyriakides: "Loss of monocyte chemoattractant protein-1 alters macrophage polarization and reduces NF?B activation in the foreign body response." in: Acta biomaterialia, Vol. 11, pp. 37-47, (2014) (PubMed).

Geng, Lan, Singha, Gilchrist, Weinreb, Violette, Weinberg, Saikumar, Venkatachalam: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." in: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).

Mortarini, Vegetti, Molla, Arienti, Ravagnani, Maurichi, Patuzzo, Santinami, Anichini: "Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 12, pp. 4085-94, (2009) (PubMed).

Synonyme und alternative Namen zu TGF-beta

transforming growth factor beta 1 (TGFB1), transforming growth factor beta-1 (TGFB1), transforming growth factor beta 1 (Tgfb1), transforming growth factor, beta 1 (Tgfb1), CED, DPD1, LAP, TGF-beta, TGF-BETA-1, TGF-beta1, TGFB, Tgfb, Tgfb-1, TGFbeta, TGFbeta1

Bezeichner auf Proteinebene für TGF-beta

  • TGF-beta 1 protein
  • TGF-beta-1
  • latency-associated peptide
  • transforming growth factor beta-1
  • transforming growth factor, beta 1 (Camurati-Engelmann disease)
  • transforming growth factor-beta 1
  • transforming growth factor beta 1
  • transforming growth factor-beta
  • transforming growth factor beta1
  • transforming growth factor-beta-1
  • TGF-beta 1
  • regulatory protein
  • transforming growth factor, beta-1
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