anti-TAB2 (TAB2) Antikörper

Bezeichnung:: anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 Antikörper (TAB2)

Auf www.antikoerper-online.de finden Sie aktuell 68 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen und TAB2 Proteine (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 85 TAB2 Produkte verfügbar.

Synonyme:: 1110030N06Rik, A530078N03Rik, CHTD2, map3k7ip2, mKIAA0733, zgc:77446

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	TAB2	23118	Q9NYJ8
	TAB2	68652	Q99K90
	TAB2	308267	Q5U303
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-TAB2 (TAB2) Antikörper

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anti-Human TAB2 Antikörper:

anti-Mouse (Murine) TAB2 Antikörper:

anti-Rat (Rattus) TAB2 Antikörper:

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Verknüpfte Pathways mit anti-TAB2 Antikörper

Toll-Like Receptors Cascades

Weitere Produktkategorien zu TAB2 Antikörper

Am meisten referenzierte anti-TAB2 Antikörper

Human Monoclonal TAB2 Primary Antibody für FACS, ELISA - ABIN969430 : Häcker, Karin: Regulation and function of IKK and IKK-related kinases. in Science's STKE : signal transduction knowledge environment 2006 (PubMed)
Show all 3 Pubmed References
Human Monoclonal TAB2 Primary Antibody für FACS, ELISA - ABIN967128 : Simmonds, Heward, Carr-Smith, Foxall, Franklyn, Gough: Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease. in The Journal of clinical endocrinology and metabolism 2006 (PubMed)
Show all 4 Pubmed References
Cow (Bovine) Polyclonal TAB2 Primary Antibody für IHC, WB - ABIN2779619 : Kanayama, Seth, Sun, Ea, Hong, Shaito, Chiu, Deng, Chen: TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. in Molecular cell 2004 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen TAB2 Interaktionspartner

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Interaktionspartner

Data indicate an association between TAK1-binding protein 2 (TAB2) mutations and a connective tissue disorder with severe polyvalvular heart disease and subtle facial dysmorphism.
The combination of WES, genomic triangulation, and systems biology has uncovered perturbations in TGF-beta activated kinase 1 (zeige MAP3K7 Antikörper) signaling as a novel pathogenic substrate for polyvalvular syndrome.
Data suggest that mRNA/protein levels of NLRP6 (zeige NLRP6 Antikörper) are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 (zeige NLRP6 Antikörper) provides docking site to facilitate interaction between TAB2/3 and TRIM38 (zeige TRIM38 Antikörper) in RA synoviocytes in response to TNFalpha (zeige TNF Antikörper). (NLRP6 (zeige NLRP6 Antikörper) = ; TAB2/3 = transforming growth factor-b (zeige ATP5S Antikörper)-activated kinase 1-binding protein 2/3; TRIM38 (zeige TRIM38 Antikörper) = tripartite motif 38)
A Novel Functional Domain of Tab2 Involved in the Interaction with Estrogen Receptor Alpha (zeige ESR1 Antikörper) in Breast Cancer Cells
The expression of miR (zeige MLXIP Antikörper)-155 target gene, TAB2, and the downstream gene, iNOS (zeige NOS2 Antikörper), were found to be inhibited in psoriatic dermal mesenchymal stem cells.
DK1 (zeige DOLK Antikörper) inhibits the formation of the TAK1 (zeige MAP3K7 Antikörper)-TAB2-TRAF6 (zeige TRAF6 Antikörper) complex and leads to the inhibition of TRAF6 (zeige TRAF6 Antikörper) ubiquitination.
Authors demonstrate that enterovirus 71 3C interacts with TAB2 and TAK1 (zeige MAP3K7 Antikörper) and suppresses cytokine expression via cleavage of the TAK1 (zeige MAP3K7 Antikörper) complex proteins.
SUMOylation may serve as a novel mechanism for the regulation of TAB2.
conclude that TRIM38 (zeige TRIM38 Antikörper) negatively regulates TNFalpha (zeige TNF Antikörper)- and IL-1beta (zeige IL1B Antikörper)-induced signaling by mediating lysosome-dependent degradation of TAB2/3, two critical components in TNFalpha (zeige TNF Antikörper)- and IL-1beta (zeige IL1B Antikörper)-induced signaling pathways
These data indicate that overexpression of TRIM22 (zeige TRIM22 Antikörper) may negatively regulate the TRAF6 (zeige TRAF6 Antikörper)-stimulated NF-kappaB (zeige NFKB1 Antikörper) pathway by interacting with and degrading TAB2.

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Interaktionspartner

These findings support a regulatory role for TGF-beta-activated kinase 1 (zeige MAP3K7 Antikörper) in governing downstream MAPKs/NF-kappaB (zeige NFKB1 Antikörper) signaling cascades in the macrophage activation in response to hyperglycemic insult
RNF4 (zeige RNF4 Antikörper) negatively regulates NF-kappaB (zeige NFKB1 Antikörper) signaling by down-regulating TAB2
TAB1 (zeige TAB1 Antikörper) and TAB2 are required for activated macrophages, making TAB1 (zeige TAB1 Antikörper) and TAB2 effective targets to control inflammation by modulating macrophage survival.
Loss of Tab2 is associated with liver injury.
miR (zeige MLXIP Antikörper)-155 inhibits the immunosuppressive capacity of MSCs by reducing iNOS (zeige NOS2 Antikörper) expression by targeting TAB2.
TAB2 and TAB3 (zeige TAB3 Antikörper) are essential for B cell activation (zeige BLNK Antikörper) leading to antigen-specific antibody responses, as well as B-1 and marginal zone B cell development.
We found that endothelial TAK1 (zeige NR2C2 Antikörper) and TAB2, but not TAB1 (zeige TAB1 Antikörper), were critically involved in vascular formation
MiR (zeige MLXIP Antikörper)-23b suppresses IL-17 (zeige IL17A Antikörper)-, tumor necrosis factor alpha (TNF-alpha (zeige TNF Antikörper))- or IL-1beta (zeige IL1B Antikörper)-induced NF-kappaB (zeige NFKB1 Antikörper) activation and inflammatory cytokine expression by targeting TAB2, TAB3 (zeige TAB3 Antikörper) and IKK-alpha (zeige CHUK Antikörper).
Epithelial TAK1 (zeige NR2C2 Antikörper) activity is regulated through two unique, TAB1 (zeige TAB1 Antikörper)-dependent basal & TAB2-mediated stimuli-dependent mechanisms.
TAK1 (zeige NR2C2 Antikörper) and its adapter protein (zeige GRB10 Antikörper), TAB2, reciprocally regulate both TAK1 (zeige NR2C2 Antikörper)- and ASK1 (zeige MAP3K5 Antikörper)-mediated signaling pathways to direct the activations of NF-kappaB (zeige NFKB1 Antikörper) and AP-1 (zeige JUN Antikörper).

Zebrafish TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Interaktionspartner

a critical, dosage-sensitive role during development was demonstrated by the cardiac defects observed upon titrated knockdown of tab2 expression in zebrafish embryos

TAB2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Alternative names and synonyms associated with TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2 (TAB2) Antikörper
TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Tab2) Antikörper
TGF-beta activated kinase 1/MAP3K7 binding protein 2 (tab2) Antikörper

1110030N06Rik Antikörper
A530078N03Rik Antikörper
CHTD2 Antikörper
map3k7ip2 Antikörper
mKIAA0733 Antikörper
zgc:77446 Antikörper

Bezeichner auf Proteinebene für TAB2

TGF-beta activated kinase 1/MAP3K7 binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2-like , TAB-2 , TAK1-binding protein 2 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 , TGF-beta-activated kinase 1-binding protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 , mitogen-activated protein kinase kinase kinase 7 interacting protein 2 , Tak1 binding protein 2 , mitogen activated protein kinase kinase kinase 7 interacting protein 2 , mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog

GENE ID	SPEZIES
100026855	Monodelphis domestica
100414129	Callithrix jacchus
100597932	Nomascus leucogenys
23118	Homo sapiens
421622	Gallus gallus
484028	Canis lupus familiaris
540203	Bos taurus
68652	Mus musculus
308267	Rattus norvegicus
494163	Danio rerio

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