Protein Überblick

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with SMAD, Mothers Against DPP Homolog 1 (SMAD1)

• SMAD family member 1 (smad1) Antikörper
• SMAD family member 1 (SMAD1) Antikörper
• Mothers against dpp (Mad) Antikörper
• SMAD family member 1 (Smad1) Antikörper
• SMAD family member 1 L homeolog (smad1.L) Antikörper

• 2/23 Antikörper
• AI528653 Antikörper
• apg Antikörper
• BSP-1 Antikörper
• BSP1 Antikörper
• Alle Synonyme
• c28 Antikörper
• CG12399 Antikörper
• dMad Antikörper
• Dmel\\CG12399 Antikörper
• E(zen)2 Antikörper
• En(vvl) Antikörper
• fb39h09 Antikörper
• JV4-1 Antikörper
• JV41 Antikörper
• l(2)k00237 Antikörper
• mad Antikörper
• Madh1 Antikörper
• Madr1 Antikörper
• Mat Antikörper
• MLP Antikörper
• Mlp1 Antikörper
• MusMLP Antikörper
• p-Mad Antikörper
• pMad Antikörper
• pSmad Antikörper
• Smad Antikörper
• smad-1 Antikörper
• smad1 Antikörper
• wu:fb39h09 Antikörper
• wu:fb97e04 Antikörper
• xmad Antikörper
• Xmad1 Antikörper
• Xsmad1 Antikörper

Bezeichner auf Proteinebene für SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1