anti-DIS3L2 (DIS3L2) Antikörper

Bezeichnung:: anti-DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 Antikörper (DIS3L2)

Auf www.antikoerper-online.de finden Sie aktuell 40 DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Antikörper von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DIS3L2 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 47 DIS3L2 Produkte verfügbar.

Synonyme:: 4930429A22Rik, 8030493P09Rik, DIS3L2, DKFZp469O0522, FAM6A, hDIS3L2, PRLMNS, RGD1560168

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	DIS3L2	367307
	DIS3L2	129563	Q8IYB7
	DIS3L2	208718	Q8CI75
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-DIS3L2 (DIS3L2) Antikörper

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anti-Rat (Rattus) DIS3L2 Antikörper:

anti-Human DIS3L2 Antikörper:

anti-Mouse (Murine) DIS3L2 Antikörper:

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Verknüpfte Pathways mit anti-DIS3L2 Antikörper

Stem Cell Maintenance

Weitere Produktkategorien zu DIS3L2 Antikörper

Am meisten referenzierte anti-DIS3L2 Antikörper

Human Monoclonal DIS3L2 Primary Antibody für FACS, IHC - ABIN1724900 : Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. in Nature genetics 2012 (PubMed)
Show all 2 Pubmed References
Human Polyclonal DIS3L2 Primary Antibody für IHC, IHC (p) - ABIN4305257 : Chang, Triboulet, Thornton, Gregory: A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. in Nature 2013 (PubMed)

Weitere Antikörper gegen DIS3L2 Interaktionspartner

Human DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Interaktionspartner

These findings suggest that sequestration of the exoribonucleases DIS3L2 and XRN1 (zeige XRN1 Antikörper) to nuclear inclusions may be related to the pathogenesis of intranuclear inclusion body disease
The evidence has been presented that Dis3l2 controls miRNA-9 production.
Our findings establish the role of DIS3L2 and oligouridylation as the cytoplasmic quality control for highly structured ncRNAs
Studies indicate important roles of the exoribonucleases DIS3L2 and XRN1 (zeige XRN1 Antikörper) in cellular function, viability and disease.
these results indicate that catalytically inactive DIS3L2, characteristic of Perlman syndrome, can lead to deregulation of its target RNAs to disturb transcriptome homeostasis.
DIS3L2 interacts with Ago2 (zeige EIF2C2 Antikörper) and governs target RNA-directed miRNA degradation.
DIS3L2 is the missing component of the LIN28 (zeige LIN28A Antikörper)-TUT4 (zeige ZCCHC11 Antikörper)/7-DIS3L2 pathway required for the repression of let-7 in pluripotent cells.
in cellular models DIS3L2 knockdown is associated with abnormalities of cell growth and division
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility.

Mouse (Murine) DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Interaktionspartner

DIS3L2 loss of function results in transcriptional activation of the Igf2/H19 (zeige NCKAP1 Antikörper) locus in nephron progenitor cells, most likely by leading to the activation of shared cis (zeige CISH Antikörper)-regulatory elements that control these genes.
Dis3l2-mediated decay is a quality control pathway for noncoding RNAs.
DIS3L2 interacts with Ago2 (zeige EIF2C2 Antikörper) and governs target RNA-directed miRNA degradation.
structure of mouse Dis3l2 in complex with an oligoU RNA to mimic the uridylated tail of pre-let-7
identification of Dis3l2 as the 3'-5' exonuclease (zeige EXOSC10 Antikörper) responsible for the decay of uridylated pre-let-7 in mouse embryonic stem cells

DIS3L2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.

Alternative names and synonyms associated with DIS3L2

DIS3-like 3'-5' exoribonuclease 2 (Dis3l2) Antikörper
DIS3 like 3'-5' exoribonuclease 2 (DIS3L2) Antikörper
DIS3-like exonuclease 2 (LOC100344728) Antikörper
DIS3 like 3'-5' exoribonuclease 2 (Dis3l2) Antikörper

4930429A22Rik Antikörper
8030493P09Rik Antikörper
DIS3L2 Antikörper
DKFZp469O0522 Antikörper
FAM6A Antikörper
hDIS3L2 Antikörper
PRLMNS Antikörper
RGD1560168 Antikörper

Bezeichner auf Proteinebene für DIS3L2

DIS3 mitotic control homolog-like 2 , DIS3-like exonuclease 2 , DIS3 mitotic control-like 2 , DIS3 mitotic control homolog (S. cerevisiae)-like 2 , DIS3-like exonuclease 2-like , family with sequence similarity 6, member A

GENE ID	SPEZIES
367307	Rattus norvegicus
519222	Bos taurus
610194	Canis lupus familiaris
100153005	Sus scrofa
424934	Gallus gallus
712905	Macaca mulatta
100064500	Equus caballus
100171476	Pongo abelii
100344728	Oryctolagus cuniculus
100398360	Callithrix jacchus
100465652	Ailuropoda melanoleuca
100540548	Meleagris gallopavo
100605598	Nomascus leucogenys
129563	Homo sapiens
208718	Mus musculus

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Show all anti-DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Antikörper with Pubmed References

Human DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Interaktionspartner

Mouse (Murine) DIS3 Mitotic Control Homolog (S. Cerevisiae)-Like 2 (DIS3L2) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with DIS3L2

Bezeichner auf Proteinebene für DIS3L2