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SRRT Proteine

(Serrate RNA Effector Molecule Homolog (SRRT))
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA)\; however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).

3 Treffer

SRRT Spezies: Human Wirt: Wheat germ Recombinant ELISA, AA, AP, WB
Produktnummer ABIN1345737
 
SRRT Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714949
 
SRRT Spezies: Chinese Hamster Wirt: Hefe Recombinant > 90 % ELISA
Produktnummer ABIN1635251
 
  • Typ Protein
    • Protein
  • Anwendung
    • ELISA
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Standard (STD)
    • Western Blotting (WB)
  • Reaktivität
    • Human
    • Chinese Hamster
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • HEK-293 Cells
    • Wheat germ
    • Yeast
  • Bindungsspezifität
    • AA 1-306
    • AA 1-429
    • Transcript Variant 1
  • Konjugat
    • GST tag
    • His tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Lyophilized
  • Hersteller
    • CUSABIO
    • OriGene
    • antibodies-online

Aliase für SRRT Proteine

Arsenic resistance protein 2 (Ars2) Proteine
serrate, RNA effector molecule S homeolog (srrt.S) Proteine
serrate, RNA effector molecule (SRRT) Proteine
serrate RNA effector molecule homolog (Arabidopsis) (Srrt) Proteine
serrate, RNA effector molecule (Srrt) Proteine
serrate RNA effector molecule homolog (Arabidopsis) (srrt) Proteine
2810019G02Rik Proteine
anon-WO0118547.166 Proteine
ars2 Proteine
ARS2 Proteine
Ars2 Proteine
ars2-A Proteine
ASR2 Proteine
Asr2 Proteine
ASR2A Proteine
ASR2B Proteine
ASR2C Proteine
ASR2D Proteine
CG7843 Proteine
CHUNP6881 Proteine
Dmel\\CG7843 Proteine
MGC92060 Proteine
serrate Proteine
zgc:92060 Proteine
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