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SPTLC2 Produkte

(serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].

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Ausgewählte SPTLC2 Kategorien

SPTLC2 Antikörper

High quality antibodies with extensive validation data.

SPTLC2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SPTLC2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SPTLC2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN564104
Menge 50 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7168896
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN1881828
Menge 400 μL
Datenblatt Datenblatt

Empfohlene SPTLC2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959377
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6232466
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SPTLC2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321285
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321284
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3109829
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SPTLC2 Produkten

Wang, Robinet, Smith, Gulshan: "ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 12, pp. 3728-33, (2015) (PubMed).

Gupta, Gable, Alexaki, Chandris, Proia, Dunn, Harmon: "Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 90-8, (2015) (PubMed).

Rotthier, Auer-Grumbach, Janssens, Baets, Penno, Almeida-Souza, Van Hoof, Jacobs, De Vriendt, Schlotter-Weigel, Löscher, Vondráček, Seeman: "Mutations in the SPTLC2 subunit of serine palmitoyltransferase cause hereditary sensory and autonomic neuropathy type I." in: American journal of human genetics, Vol. 87, Issue 4, pp. 513-22, (2010) (PubMed).

Han, Gupta, Gable, Niranjanakumari, Moitra, Eichler, Brown, Harmon, Dunn: "Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 20, pp. 8186-91, (2009) (PubMed).

Chen, Han, Dietrich, Dunn, Cahoon: "The essential nature of sphingolipids in plants as revealed by the functional identification and characterization of the Arabidopsis LCB1 subunit of serine palmitoyltransferase." in: The Plant cell, Vol. 18, Issue 12, pp. 3576-93, (2007) (PubMed).

Hornemann, Wei, von Eckardstein: "Is the mammalian serine palmitoyltransferase a high-molecular-mass complex?" in: The Biochemical journal, Vol. 405, Issue 1, pp. 157-64, (2007) (PubMed).

Stachowitz, Alessandrini, Abeck, Ring, Behrendt: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).

Dias Neto, Correa, Verjovski-Almeida, Briones, Nagai, da Silva, Zago, Bordin, Costa, Goldman, Carvalho, Matsukuma, Baia, Simpson, Brunstein, de Oliveira, Bucher, Jongeneel, OHare, Soares, Brentani et al.: "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 7, pp. 3491-6, (2000) (PubMed).

Synonyme und alternative Namen zu SPTLC2

serine palmitoyltransferase long chain base subunit 2 (SPTLC2), serine palmitoyltransferase 2 (LOC100446763), serine palmitoyltransferase long chain base subunit 2 (sptlc2), serine palmitoyltransferase, long chain base subunit 2 S homeolog (sptlc2.S), serine palmitoyltransferase, long chain base subunit 2a (sptlc2a), serine palmitoyltransferase, long chain base subunit 2 (Sptlc2), serine palmitoyltransferase long chain base subunit 2 (Sptlc2), AI173915, hLCB2a, HSN1C, LCB2, LCB2A, LCB2a, mKIAA0526, NSAN1C, Pomt2, SPT2, sptlc2, SPTLC2, zgc:110661

Bezeichner auf Proteinebene für SPTLC2

  • LCB 2
  • SPT 2
  • long chain base biosynthesis protein 2a
  • serine palmitoyltransferase 2
  • serine palmitoyltransferase, subunit II
  • serine-palmitoyl-CoA transferase 2
  • serine palmitoyltransferase, long chain base subunit 2
  • serine palmitoyltransferase 2-like
  • LCB2a
  • long chain base biosynthesis protein 2
  • protein-O-mannosyltransferase 2
  • Long chain base biosynthesis protein 2
  • Long chain base biosynthesis protein 2a
  • Serine-palmitoyl-CoA transferase 2
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