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SPINK1 Produkte

(serine Peptidase Inhibitor, Kazal Type 1 (SPINK1))
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008].

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Ausgewählte SPINK1 Kategorien

SPINK1 Antikörper

High quality antibodies with extensive validation data.

SPINK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SPINK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SPINK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation IHC (p), IP, ELISA, WB
Validierungen
  • (8)
  • (5)
Kat. Nr. ABIN562978
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7168925
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, ICC, IF, IHC, WB
Validierungen
  • (3)
Kat. Nr. ABIN6265260
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SPINK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6959380
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1889398
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962684
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SPINK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3082240
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3132660
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2732592
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SPINK1 Produkten

Hellmann, Paiella, Kostro, Marek, Adrych, Śledziński, Hać, Bassi: "Surgical decompression of Wirsung duct reduces serum concentration of SPINK1 in patients with chronic pancreatitis." in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 18, Issue 3, pp. 275-279, (2018) (PubMed).

Mehner, Oberg, Kalli, Nassar, Hockla, Pendlebury, Cichon, Goergen, Maurer, Goode, Keeney, Jatoi, Sahin-Tóth, Copland, Radisky, Radisky: "Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers." in: Oncotarget, Vol. 6, Issue 34, pp. 35737-54, (2016) (PubMed).

Palanisamy, Tsodikov, Yan, Suleman, Rittmaster, Lucia, Chinnaiyan, Fleshner, Kunju: "Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial." in: Urologic oncology, Vol. 33, Issue 3, pp. 108.e5-108.e13, (2015) (PubMed).

Ateeq, Kunju, Carskadon, Pandey, Singh, Pradeep, Tandon, Singhai, Goel, Amit, Agarwal, Dinda, Seth, Tsodikov, Chinnaiyan, Palanisamy: "Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India." in: The Prostate, Vol. 75, Issue 10, pp. 1051-62, (2015) (PubMed).

Zhang, Wang, Hu, Wang, Yu, Wang: "The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line." in: Tumour biology, (2015) (PubMed).

El-mezayen, Metwally, Darwish: "A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer." in: Tumour biology, Vol. 35, Issue 3, pp. 2759-67, (2014) (PubMed).

Smith, Palanisamy, Zuhlke, Johnson, Siddiqui, Chinnaiyan, Kunju, Cooney, Tomlins: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." in: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, (2014) (PubMed).

Wang, Wang, Su, Lu, Song, Yang, Fu, Tan, Han: "Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer." in: The Prostate, Vol. 74, Issue 7, pp. 689-701, (2014) (PubMed).

Rink, Park, Volkmer, Xylinas, Hansen, Cha, Robinson, Hautmann, Küfer, Engel, Chun, Dahlem, Rubin, Shariat, Mosquera: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." in: Urologic oncology, Vol. 31, Issue 8, pp. 1716-24, (2013) (PubMed).

Bhalla, Kunju, Tomlins, Christopherson, Cortez, Carskadon, Siddiqui, Park, Mosquera, Pestano, Rubin, Chinnaiyan, Palanisamy: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, (2013) (PubMed).

Synonyme und alternative Namen zu SPINK1

serine peptidase inhibitor, Kazal type 1 (SPINK1), serine peptidase inhibitor, Kazal type 1 (Spink1), p12, PCTT, PSTI, Psti, SPINK1, Spink3, TATI, TCP

Bezeichner auf Proteinebene für SPINK1

  • pancreatic secretory trypsin inhibitor
  • serine protease inhibitor Kazal-type 1
  • serine protease inhibitor, Kazal type 1
  • tumor-associated trypsin inhibitor
  • PSTI-II
  • calcium transport inhibitor
  • caltrin
  • pancreatic secretory trypsin inhibitor II
  • pancreatic secretory trypsin inhibitor type II (PSTI-II)
  • serine peptidase inhibitor, Kazal type 3
  • serine protease inhibitor Kazal-type 3
  • serine protease inhibitor, Kazal type 3
  • serine peptidase inhibitor, Kazal type 1
  • prostatic secretory glycoprotein
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