SPANXB1 Produkte
(SPANX Family, Member B1 (SPANXB1))
Kategorien
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008].
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Ausgewählte SPANXB1 Kategorien
SPANXB1 Antikörper
High quality antibodies with extensive validation data.
Empfohlene SPANXB1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN1881824
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN531836
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
Kat. Nr.
ABIN531837
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene SPANXB1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6234137
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SPANXB1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7546346
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321076
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPANXB1 Produkten
: "SPANX gene variation in fertile and infertile males." in: Systems biology in reproductive medicine, Vol. 55, pp. 18-26, (2010) (PubMed).: "A shared promoter region suggests a common ancestor for the human VCX/Y, SPANX, and CSAG gene families and the murine CYPT family." in: Molecular reproduction and development, Vol. 75, Issue 2, pp. 219-29, (2007) (PubMed).
: "Dynamic structure of the SPANX gene cluster mapped to the prostate cancer susceptibility locus HPCX at Xq27." in: Genome research, Vol. 15, Issue 11, pp. 1477-86, (2005) (PubMed).
: "The human SPANX multigene family: genomic organization, alignment and expression in male germ cells and tumor cell lines." in: Gene, Vol. 309, Issue 2, pp. 125-33, (2003) (PubMed).
Synonyme und alternative Namen zu SPANXB1
SPANX family member B1 (SPANXB1), B1, CT11.2, SPANX-B, SPANXBBezeichner auf Proteinebene für SPANXB1
- SPANX family member B/F
- cancer/testis antigen 11.2
- cancer/testis antigen family 11, member 2
- nuclear-associated protein SPAN-Xb
- nuclear-associated protein SPAN-Xf
- sperm protein associated with the nucleus on the X chromosome B/F
- sperm protein associated with the nucleus, X chromosome, family member B1
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