SOCS3 Produkte
(Suppressor of Cytokine Signaling 3 (SOCS3))
Kategorien
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008].
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Ausgewählte SOCS3 Kategorien
SOCS3 Antikörper
High quality antibodies with extensive validation data.
SOCS3 ELISA Kits
Reliable ELISA kits for a wide range of species.
SOCS3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SOCS3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN3021100
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF, IHC (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN522456
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (4)
- (2)
Kat. Nr.
ABIN670416
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SOCS3 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
- (1)
Kat. Nr.
ABIN6959767
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959768
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970484
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SOCS3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1320930
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125255
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3131674
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SOCS3 Produkten
: "Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 3, pp. 4718-4731, (2021) (PubMed).: "Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics." in: JCI insight, Vol. 4, Issue 20, (2020) (PubMed).
: "Olmesartan attenuates type 2 diabetes-associated liver injury: Cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways." in: European journal of pharmacology, Vol. 874, pp. 173010, (2020) (PubMed).
: "SOCS3-deficient lung epithelial cells uptaking neutrophil-derived SOCS3 worsens lung influenza infection." in: Molecular immunology, Vol. 125, pp. 51-62, (2020) (PubMed).
: "The FXR Agonist, Obeticholic Acid, Suppresses HCC Proliferation & Metastasis: Role of IL-6/STAT3 Signalling Pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 12502, (2019) (PubMed).
: "Endogenous peroxidases in sputum interfere with horse-radish peroxidase-based ELISAs." in: Journal of immunological methods, Vol. 454, pp. 76-79, (2018) (PubMed).
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." in: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).
: "MicroRNA-30c-5p ameliorates hypoxia-reoxygenation-induced tubular epithelial cell injury via HIF1α stabilization by targeting SOCS3." in: Oncotarget, Vol. 8, Issue 54, pp. 92801-92814, (2017) (PubMed).
: "Alveolar Epithelial Cell-Derived Prostaglandin E2 Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 12, pp. 5112-20, (2016) (PubMed).
: "SOCS3 blocks HIF-1? expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3." in: Molecular medicine reports, Vol. 12, Issue 1, pp. 83-92, (2015) (PubMed).
Synonyme und alternative Namen zu SOCS3
suppressor of cytokine signaling 3a (socs3a), suppressor of cytokine signaling 3 S homeolog (socs3.S), suppressor of cytokine signaling 3 (socs3), suppressor of cytokine signaling 3 L homeolog (socs3.L), suppressor of cytokine signaling 3 (SOCS3), suppressor of cytokine signaling 3a (socs3), suppressor of cytokine signaling 3 (Socs3), atod4, ATOD4, cis3, CIS3, Cis3, cish3, Cish3, EF-10, Ef10, fj09e12, MGC64393, MGC75749, MGC81248, socs-3, SOCS-3, Socs-3, socs3, SOCS3, ssi-3, SSI-3, Ssi-3, ssi3, SSI3, Ssi3, wu:fj09e12, xsocs3, zgc:56537Bezeichner auf Proteinebene für SOCS3
- suppressor of cytokine signaling 3
- suppressor of cytokine signaling 3a
- STAT-induced STAT inhibitor 3
- cytokine-inducible SH2 protein 3
- cytokine signaling suppressor
- SOCS-3
- CIS-3
- E2a-Pbx1 target gene in fibroblasts 10
- cytokine inducible SH2-containing protein 3
- suppressors of cytokine signaling 3
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