SNCA Proteine
(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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53 Treffer
SNCA
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
SNCA
Spezies: Red-chested mustached Tamarin (Saguinus labiatus)
Wirt: Hefe
Recombinant
> 90 %
ELISA
SNCA
Spezies: Primate (Erythrocebus)
Wirt: Hefe
Recombinant
> 90 %
ELISA
Aktuelle Publikationen für unsere SNCA Proteine
: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).
: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).
: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).
Aliase für SNCA Proteine
synuclein alpha L homeolog (snca.L) Proteinealpha-synuclein (LOC619283) Proteine
synuclein alpha (SNCA) Proteine
synuclein, alpha (Snca) Proteine
synuclein alpha (Snca) Proteine
alphaSYN Proteine
LOC619283 Proteine
MGC64356 Proteine
NACP Proteine
PARK1 Proteine
PARK4 Proteine
PD1 Proteine
snca Proteine
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- SNRK Proteine
- SNRNP25 Proteine
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- SNRNP35 Proteine
- SNRNP40 Proteine
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- SNRNP70 Proteine
- SNRPB Proteine
- SNRPB2 Proteine
- SNRPC Proteine
- SNRPD1 Proteine
- SNRPD2 Proteine
- SNRPD3 Proteine
- SNRPE Proteine
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