SNCA Protein (E46K)
Kurzübersicht für SNCA Protein (E46K) (ABIN7316762)
Target
Alle SNCA Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
Güteklasse
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Proteineigenschaft
- E46K
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Verwendungszweck
- Human Alpha-Synuclein (E46K) Protein, Tag Free (MALS verified)
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Sequenz
- Met 1 - Ala 140
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Produktmerkmale
- Human Alpha-Synuclein (E46K), Tag Free is expressed from E.coli cells. It contains AA Met 1 - Ala 140 (Accession # P37840-1 (E46K).
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Endotoxin-Niveau
- 1.0 EU per μg
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Synuclein, alpha (SNCA) (full length) (Active) protein
SNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (A53T) (Active) proteinSNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) proteinSNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % SDS
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (AA 1-140) protein (His-IF2DI Tag)SNCA Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Synuclein, alpha (SNCA) (active) proteinSNCA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Synuclein, alpha (SNCA) (AA 1-140) (Active) proteinSNCA Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. ELISA Active
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Kommentare
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This protein carries no "tag". The protein has a calculated MW of 14.5 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 50 mM HEPES, 100 mM NaCl, pH 8.0
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Lagerung
- -80 °C
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Informationen zur Lagerung
- -70°C
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- SNCA (Synuclein, alpha (SNCA))
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Andere Bezeichnung
- Alpha-Synuclein
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Hintergrund
- Synonyms:N/A,Description:Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
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Molekulargewicht
- 14.5 kDa
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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