SLC22A1 Produkte
(Solute Carrier Family 22 (Organic Cation Transporter), Member 1 (SLC22A1))
Kategorien
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008].
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Ausgewählte SLC22A1 Kategorien
SLC22A1 Antikörper
High quality antibodies with extensive validation data.
SLC22A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SLC22A1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SLC22A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, FACS
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN969400
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7075663
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7170131
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SLC22A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr.
ABIN5648541
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6210854
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SLC22A1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7555346
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7562230
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7423393
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SLC22A1 Produkten
: "Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173474, (2017) (PubMed).: "Organic anion transporting polypeptide 1B3 can form homo- and hetero-oligomers." in: PLoS ONE, Vol. 12, Issue 6, pp. e0180257, (2017) (PubMed).
: "Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport." in: American journal of human genetics, Vol. 101, Issue 4, pp. 489-502, (2017) (PubMed).
: "The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin." in: Scientific reports, Vol. 6, pp. 20508, (2016) (PubMed).
: "Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1." in: Genome medicine, Vol. 7, Issue 1, pp. 56, (2015) (PubMed).
: "The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier." in: Molecular pharmaceutics, Vol. 11, Issue 3, pp. 995-1006, (2014) (PubMed).
: "Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 6, pp. 990-5, (2014) (PubMed).
: "OCT1 (SLC22A1) R61C polymorphism and response to imatinib treatment in chronic myeloid leukemia patients." in: Leukemia & lymphoma, Vol. 49, Issue 11, pp. 2222-3, (2008) (PubMed).
: "Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells." in: Pharmaceutical research, Vol. 25, Issue 4, pp. 827-35, (2008) (PubMed).
: "Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia." in: Blood, Vol. 112, Issue 8, pp. 3348-54, (2008) (PubMed).
Synonyme und alternative Namen zu SLC22A1
solute carrier family 22 member 1 (SLC22A1), solute carrier family 22 (organic cation transporter), member 1 (Slc22a1), solute carrier family 22 member 1 (Slc22a1), solute carrier family 22 member 2-like (LOC421584), HOCT1, Lx1, OCT1, Oct1, oct1_cds, Orct, Orct1, Roct1, SLC22A1, SLC22A2Bezeichner auf Proteinebene für SLC22A1
- solute carrier family 22 member 1
- solute carrier family 22 (organic cation transporter), member 1
- solute carrier family 22 member 1-like
- pOCT1
- organic cation transporter 1
- mOCT1
- solute carrier family 22, member 1
- solute carrier family 22 (organic cation transporter), member 2
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