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SIRT1 Antikörper

(Sirtuin 1 (SIRT1))

SIRT1 (Sirtuin 1) is a protein that plays a role in regulating metabolism and has been implicated in the development and progression of obesity. Several studies have investigated the potential of targeting SIRT1 as a therapeutic strategy for obesity.

Research has shown that SIRT1 is involved in the regulation of nutrient sensing and can modulate lipid and glucose metabolism. It has been found to protect against high-fat diet-induced metabolic damage and hepatic lipid accumulation. SIRT1 has also been shown to promote lipid metabolism and mitochondrial function, which are important processes in adipogenesis and obesity.

In addition, SIRT1 has been found to counteract aging- and obesity-related diseases by deacetylating many proteins. It has been suggested that targeting SIRT1 activity in the brain may show promise for the treatment of obesity and associated metabolic disorders.

SIRT1 antibodies are essential research tools for better understanding the role of SIRT1 in in regulating metabolism, lipid metabolism, and mitochondrial function.

178 Treffer

SIRT1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN7646194
 
SIRT1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7160852
 
SIRT1 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7160854
 
SIRT1 Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7160853
 
SIRT1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C2 unconjugated
Produktnummer ABIN7428617
 
SIRT1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7646193
 
SIRT1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN729855
 
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN745660
 
SIRT1 Reaktivität: Human, Maus, Hund WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN679030
 
SIRT1 Reaktivität: Human, Maus WB, IHC, ELISA, IP Wirt: Maus Monoclonal 6A1 unconjugated
Produktnummer ABIN7119109
 
SIRT1 Reaktivität: Human, Maus, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5010563
 
SIRT1 Reaktivität: Human, Maus, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5010562
 
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5010560
 
SIRT1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5010559
 
SIRT1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN5010558
 
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 750
Produktnummer ABIN5010561
 
SIRT1 Reaktivität: Human, Maus, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2806383
 
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2806381
 
SIRT1 Reaktivität: Human, Maus, Ratte WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2806380
 
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, FACS, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN876312
 
  • Typ Primary
    • Primary
  • Anwendung
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Chromatin Immunoprecipitation (ChIP)
    • Radioimmunoassay (RIA)
    • Immunochromatography (IC)
    • Proximity Ligation Assay (PLA)
    • Coating (Coat)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Dog
    • Monkey
    • Rabbit
    • Chicken
    • Cow
    • Guinea Pig
    • Horse
    • Zebrafish (Danio rerio)
    • Bat
    • Pig
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Nur ohne Konservierungsmittel
  • Carrier free only
  • Wirt
    • Rabbit
    • Mouse
    • Chicken
    • Goat
    • Sheep
  • Klonalität
    • Polyclonal
    • Monoclonal
  • Klon
    • C2
    • 1089CT5-3-1
    • 1F3
    • 7B7
    • 9E9
    • D4
    • 2G1-F7
    • 2G10-F4-D9
    • 3C7
    • 6A1
    • 6H5
    • FDA-19
    • GG-19
    • HAI-19
    • PT0158R
    • PT0764R
    • R06-4K9
    • RB50965
  • Bindungsspezifität
    • pSer47
    • AA 101-200
    • AA 551-650
    • AA 244-498
    • pThr530
    • C-Term
    • AA 2-747
    • AA 254-495
    • N-Term
    • AA 456-555
    • AA 236-490
    • AA 238-482
    • AA 25-75
    • AA 566-601
    • Ser47
    • AA 1-180
    • AA 1-490
    • AA 112-311
    • AA 13-62
    • AA 142-533
    • AA 194-747
    • AA 207-256
    • AA 30-110
    • AA 41-90
    • AA 448-747
    • AA 551-599
    • AA 577-590
    • AA 581-630
    • AA 587-621
    • AA 686-721
    • AA 700-747
    • Internal Region
    • Tyr631
    • pSer27
  • Konjugat
    • Unkonjugiert
    • Biotin
    • FITC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
    • PE
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • APC
    • PerCP
  • Isotyp
    • IgG
    • IgG1
    • Ig Fraction
    • IgG1 kappa
    • IgG3 kappa
    • kappa
    • IgG2b
    • IgG2b kappa
    • IgY
  • Protein-Typ
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
    • KO Validated
  • Hersteller
    • antibodies-online
    • Signalway
    • Biomatik
    • Assaypro
    • Abbexa
    • Boster Bio
    • NSJ Bioreagents
    • FabGennix
    • Acris
    • Rockland
    • Active Motif
    • Angio-Proteomie
    • Assay Biotechnology Company, Inc.
    • Aviva Systems Biology
    • Cloud-Clone
    • Cohesion Biosciences
    • Elabscience

Aktuelle Publikationen für unsere SIRT1 Antikörper

Zbroch, Bazyluk, Malyszko, Koc-Zorawska, Rydzewska-Rosolowska, Kakareko, Hryszko: "The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis." in: Clinical interventions in aging, Vol. 15, pp. 387-393, (2020) (PubMed).

Yang, Wang, He, Liu, Chen, Wang, Wang, Wang: "Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1." in: Frontiers in pharmacology, Vol. 11, pp. 1136, (2020) (PubMed).

Ascenzi, Barberi, Dobrowolny, Villa Nova Bacurau, Nicoletti, Rizzuto, Rosenthal, Scicchitano, Musarò: "Effects of IGF-1 isoforms on muscle growth and sarcopenia." in: Aging cell, Vol. 18, Issue 3, pp. e12954, (2019) (PubMed).

Takata, Sakasai-Sakai, Takino, Takeuchi: "Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver." in: Nutrients, Vol. 11, Issue 7, (2019) (PubMed).

Yanes, Zhang, Shen, Weyand, Goronzy: "Metabolic reprogramming in memory CD4 T cell responses of old adults." in: Clinical immunology (Orlando, Fla.), Vol. 207, pp. 58-67, (2019) (PubMed).

Zhang, Abdukerim, Abilailieti, Tang, Ling, Pan: "The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells." in: Archives of biochemistry and biophysics, Vol. 672, pp. 108052, (2019) (PubMed).

Piao, Zhao, Zhu, Inoue, Shibata, Lei, Hu, Yu, Yang, Wu, Xu, Okumura, Ouchi, Murohara, Kuzuya, Cheng: "Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis." in: Journal of the American Heart Association, Vol. 6, Issue 10, (2018) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Zeng, Hu, He, Wang, Li, Xiong, Ye: "Hypothermic machine perfusion ameliorates inflammation during ischemia‑reperfusion injury via sirtuin‑1‑mediated deacetylation of nuclear factor‑κB p65 in rat livers donated after circulatory death." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8649-8656, (2018) (PubMed).

Zhang, Zhang, Guo, Zeng, Wu, Liu, He, Wang, Huang, Chen: "Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 4082102, (2018) (PubMed).

Aliase für SIRT1 Antikörper

sirtuin 1 (SIRT1) Antikörper
sirtuin 1 (SRT1) Antikörper
sirtuin 1 (Sirt1) Antikörper
sirtuin 1 L homeolog (sirt1.L) Antikörper
AA673258 Antikörper
Sir2 Antikörper
SIR2 Antikörper
Sir2a Antikörper
Sir2alpha Antikörper
SIR2L1 Antikörper
sir2l1 Antikörper
sirtuin Antikörper
sirtuin 1 Antikörper
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