SIGMAR1 Produkte
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Kategorien
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor\; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008].
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Ausgewählte SIGMAR1 Kategorien
SIGMAR1 Antikörper
High quality antibodies with extensive validation data.
SIGMAR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIGMAR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SIGMAR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN389221
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7261441
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7236046
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene SIGMAR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN1058417
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Dog
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN1058418
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Chicken
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN1058419
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SIGMAR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1790001
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3076948
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN3131914
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SIGMAR1 Produkten
: "Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2018) (PubMed).: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).
: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." in: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).
: "The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands." in: The Biochemical journal, Vol. 466, Issue 2, pp. 263-71, (2015) (PubMed).
: "Modeling tandem AAG8-MEK inhibition in melanoma cells." in: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).
: "Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances." in: Cell death & disease, Vol. 5, pp. e1290, (2014) (PubMed).
: "Sigma-1 receptor enhances neurite elongation of cerebellar granule neurons via TrkB signaling." in: PLoS ONE, Vol. 8, Issue 10, pp. e75760, (2013) (PubMed).
: "Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis." in: Human molecular genetics, Vol. 22, Issue 8, pp. 1581-600, (2013) (PubMed).
: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).
: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).
Synonyme und alternative Namen zu SIGMAR1
sigma non-opioid intracellular receptor 1 (SIGMAR1), sigma non-opioid intracellular receptor 1 (Sigmar1), sigma non-opioid intracellular receptor 1 L homeolog (sigmar1.L), sigma non-opioid intracellular receptor 1 (sigmar1), AL024364, ALS16, mSigmaR1, OPRS1, Oprs1, oprs1, SIG-1R, sigma1R, Sigma1R, SR-BP, SR-BP1, SRBP, zgc:56378Bezeichner auf Proteinebene für SIGMAR1
- SR31747 binding protein 1
- aging-associated gene 8 protein
- hSigmaR1
- sigma 1-type opioid receptor
- opioid receptor, sigma 1
- sigma1-receptor
- sigma1R
- Sigma 1-type opioid receptor
- Sigma1-receptor
- sigma1-receptor (sterol-isomerase like protein)
- sterol isomerase-like protein
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