anti-Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Antikörper

Bezeichnung:: anti-Gap Junction Protein, gamma 3, 30.2kDa Antikörper (GJc3)

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Synonyme:: CX29, CX30.2, CX31.3, GJE1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	GJc3	118446	Q921C1
	GJc3	288529
	GJc3	349149	Q8NFK1
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Verknüpfte Pathways mit anti-Gap Junction Protein, gamma 3, 30.2kDa Antikörper

Sensory Perception of Sound

Am meisten referenzierte anti-Gap Junction Protein, gamma 3, 30.2kDa Antikörper

Dog (Canine) Polyclonal GJc3 Primary Antibody für ELISA - ABIN4274141 : Sargiannidou, Ahn, Enriquez, Peinado, Reynolds, Abrams, Scherer, Kleopa: Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants. in Neurobiology of disease 2008 (PubMed)

Weitere Antikörper gegen Gap Junction Protein, gamma 3, 30.2kDa Interaktionspartner

Mouse (Murine) Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Interaktionspartner

Comparative mapping of Y1 and Y5 receptor (zeige NPY5R Antikörper) subtypes within cell bodies and nerve fibers in the brain. Together with physiological and electrophysiological studies, provides better understanding of NPY (zeige NPY Antikörper) neural circuitries.
Thus, in contrast to connexin32 (zeige GJB1 Antikörper) and connexin47, which are also expressed in myelinating cells, Cx29 does not contribute to the function of myelin in adult mice.
Homomeric interactions of Cx29 and Cx32 (zeige GJB1 Antikörper) require other domains: the N-terminus, transmembrane domains, and extracellular loops. Substituting the intracellular loop and/or tail of Cx32 (zeige GJB1 Antikörper) with those of Cx29 prevents Cx32 (zeige GJB1 Antikörper) from forming functional gap junctions.
Cx23 seems to share functional properties with pannexin (hemi) channels rather than gap junction channels of other connexins.

Human Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Interaktionspartner

Based on these findings, we suggest that p.W77S mutant has a dominant negative effect on the formation and function of the gap junction. These results give a novel molecular elucidation for the mutation of GJC3 in the development of hearing loss.
Although p.R15G and p.L23H mutants do not decrease the trafficking of CX proteins, mutations in GJC3 genes result in a loss of hemichannel function of CX30.2/CX31.3 protein, possibly causing hearing loss.
Cx31.3 is localized to the gray matter along small myelinated fibers and is co-expressed with Cx32 (zeige GJB1 Antikörper) in oligodendrocytes.

Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Antigen-Profil

Beschreibung des Gens

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.

Alternative names and synonyms associated with Gap Junction Protein, gamma 3, 30.2kDa (GJc3)

gap junction gamma-3 protein (LOC100349037) Antikörper
gap junction protein, gamma 3 (Gjc3) Antikörper
gap junction protein gamma 3 (GJC3) Antikörper

CX29 Antikörper
CX30.2 Antikörper
CX31.3 Antikörper
GJE1 Antikörper

Bezeichner auf Proteinebene für GJc3

gap junction protein, gamma 3, 30.2kDa , connexin 29 , connexin-29 , gap junction epsilon-1 protein , gap junction gamma-3 protein , gap junction membrane channel protein epsilon 1 , connexin-30.2 , connexin-31.3

GENE ID	SPEZIES
100349037	Oryctolagus cuniculus
118446	Mus musculus
288529	Rattus norvegicus
349149	Homo sapiens
539991	Bos taurus

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Show all anti-Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Antikörper with Pubmed References

Mouse (Murine) Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Interaktionspartner

Human Gap Junction Protein, gamma 3, 30.2kDa (GJc3) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Gap Junction Protein, gamma 3, 30.2kDa (GJc3)

Bezeichner auf Proteinebene für GJc3