Rekombinanter Kaninchen anti-Human lambda (full length), (Light Chain) Antikörper

Produktnummer ABIN7879496

Kurzübersicht für Rekombinanter Kaninchen anti-Human lambda (full length), (Light Chain) Antikörper (ABIN7879496)

Target: lambda

Antikörpertyp: Recombinant Antibody

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: LLC-3774R

Isotyp: IgG

Produktdetails

Bindungsspezifität: full length, Light Chain

Reaktivität: Human

Wirt: Kaninchen

Verwendungszweck: Recombinant Lambda Light Chain Antibody

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human IGL protein was used as the immunogen for the recombinant Lambda Light Chain antibody.

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Lambda Light Chain antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Lambda Light Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: lambda

Hintergrund: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01701, P01842