Rekombinanter Kaninchen anti-Human lambda (AA 1-200), (Light Chain) Antikörper

Produktnummer ABIN7879488

Kurzübersicht für Rekombinanter Kaninchen anti-Human lambda (AA 1-200), (Light Chain) Antikörper (ABIN7879488)

Target: lambda

Antikörpertyp: Recombinant Antibody

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IGL-9397R

Isotyp: IgG, kappa

Produktdetails

Bindungsspezifität: AA 1-200, Light Chain

Reaktivität: Human

Wirt: Kaninchen

Verwendungszweck: Recombinant Lambda Light Chain Antibody / IGL (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 1-200) of human Lambda light chain protein was used as the immunogen for the recombinant Lambda Light Chain antibody.

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Lambda Light Chain antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Lambda Light Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: lambda

Hintergrund: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01701