Maus anti-Human IgD (full length) Antikörper

Produktnummer ABIN7878395

Kurzübersicht für Maus anti-Human IgD (full length) Antikörper (ABIN7878395)

Target: IgD

Klonalität: Monoklonal

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IgD26

Isotyp: IgG1, kappa

Produktdetails

Bindungsspezifität: full length

Reaktivität: Human

Wirt: Maus

Verwendungszweck: Human IgD Antibody / Heavy chain (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Full length recombinant human IGHD protein was used as the immunogen for the human IgD antibody.

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the human IgD antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the human IgD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: IgD

Substanzklasse: Antibody

Hintergrund: Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

UniProt: P01880