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Ziege anti-Human IgA (Free & Bound), (Secretory Component) Antikörper

IP, ID Polyclonal unconjugated
Produktnummer ABIN568608

Kurzübersicht für Ziege anti-Human IgA (Free & Bound), (Secretory Component) Antikörper (ABIN568608)

Target

IgA

Klonalität

  • 307
  • 72
Polyklonal

Applikation

  • 194
  • 145
  • 130
  • 107
  • 107
  • 104
  • 61
  • 47
  • 46
  • 34
  • 28
  • 26
  • 23
  • 17
  • 16
  • 16
  • 14
  • 7
  • 7
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunoprecipitation (IP), Immunodiffusion (ID)
  • Bindungsspezifität

    • 69
    • 61
    • 38
    • 17
    • 15
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Free & Bound, Secretory Component

    Reaktivität

    • 188
    • 61
    • 45
    • 16
    • 15
    • 13
    • 13
    • 12
    • 12
    • 11
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human

    Wirt

    • 200
    • 109
    • 58
    • 17
    • 14
    • 6
    • 2
    Ziege

    Aufreinigung

    Serum

    Immunogen

    Secretory component is present in human secretions bound to secretory IgA (sIgA) and in free form. Secretory IgA (sIgA) functions as a dimer or polymer and accounts for almost all specific mucosal antibody activity. A molecule of sIgA is made up of two molecules of IgA, one J chain and one SC (MW 65,000). The dimer IgA is transported into secretions by its binding to the SC on the epithelial cells. Under normal conditions, sIgA contains both subclasses IgA1 and IgA2, since both are capable of binding SC. SC also has an affinity for polymeric IgM. Purified free human secretory component isolated from pooled milk is used for immunization. Freund's complete adjuvant is used in the first step of the immunization procedure.
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Restore by adding 0.5 mLsterile distilled water. Dilutions may be prepared by adding PBS, pH 7.2

    Handhabung

    Avoid repeated freezing and thawing.
    Dilutions may be prepared by adding PBS, pH 7.2

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Prior to and following reconstitution store the antibody at 2-8 °C for one month or at -28 °C for longer.
  • Target

    IgA

    Substanzklasse

    Antibody

    Hintergrund

    Synonyms: Human Immunoglobulin A
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