Maus anti-Human IgE (Chain epsilon) Antikörper

Produktnummer ABIN492638

Kurzübersicht für Maus anti-Human IgE (Chain epsilon) Antikörper (ABIN492638)

Target: IgE

Klonalität: Monoklonal

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Klon: HP6029

Isotyp: IgG2a

Produktdetails

Bindungsspezifität: Chain epsilon

Reaktivität: Human

Wirt: Maus

Aufreinigung: Purified

Anwendungsinformationen

Applikationshinweise: ELISA. Western blottingDot- and slot-immunoblotting. Immunocytochemistry. Immunohistochemistry on Ffrozen Sections.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.2 without preservatives or amine-containing buffer salts.

Konservierungsmittel: Without preservative

Handhabung: Monoclonal antibodies should not be stored at a temperature below -25 °C due to the aggregation effect of the protein.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C

Antigendetails

Target: IgE

Substanzklasse: Antibody

Hintergrund: IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/mL, compared to 10 mg/mL for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.Synonyms: Immunoglobulin E human