(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008].
serpin A3-5 (LOC396684) Proteine serpin family A member 3 (SERPINA3) Proteine alpha-1-antiproteinase F precursor (LOC100008973) Proteine serpin family A member 1 (SERPINA1) Proteine serpin family A member 1 (Serpina1) Proteine serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) Proteine serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) Proteine serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog (serpina3.L) Proteine A1AT Proteine AACT Proteine AAT Proteine ACT Proteine alpha-1-PI Proteine GIG25 Proteine PI Proteine Pi Proteine Pi2 Proteine serpina3 Proteine SERPINA3-1 Proteine SERPINA3-5 Proteine Spi1 Proteine